鞍区脑膜瘤的临床特征及手术治疗策略

发布时间：2018-06-13 13:30

本文选题：鞍区脑膜瘤 + 临床特征　；参考：《重庆医科大学》2014年硕士论文

【摘要】：目的：探讨鞍区脑膜瘤的临床特征及手术治疗策略。方法：回顾性分析我院经手术治疗鞍区脑膜瘤49例临床资料,比较鞍上型与鞍旁型脑膜瘤的临床特征，对比单侧额下入路与翼点入路的差异，总结鞍区脑膜瘤手术治疗策略。结果：鞍上型21例，鞍旁型28例，鞍上型脑膜瘤对视力、视野的影响及对垂体、视神经压迫较鞍旁型更常见（P 0.05）。49例鞍区脑膜瘤，按simpson分级标准全切33例，次全切14例，部分切除2例，全切率为67.3%。单侧额下入路与翼点入路相比，术中出血量、手术时间及术后住院时间均无差异（P0.05）。结论：鞍上型与鞍旁型脑膜瘤的临床特点具有差异，前者对视力、视野的影响及对垂体、视神经压迫更常见。在保留患者神经功能及生活质量的基础上，，最大程度切除肿瘤是主要目的，单侧额下入路及翼点入路均能使鞍区肿瘤获得良好暴露，对比术中出血量、手术时间及住院时间无明显差异。
[Abstract]:Objective: to investigate the clinical features and surgical treatment of Sellar meningioma. Methods: the clinical data of 49 patients with Sellar meningioma were analyzed retrospectively. The clinical characteristics of suprasellar meningioma and parasellar meningioma were compared, the differences between unilateral subfrontal approach and pterional approach were compared, and the surgical treatment strategies of Sellar meningioma were summarized. Results: there were 21 cases of suprasellar type, 28 cases of parasellar type, the effect of suprasellar meningioma on visual acuity, visual field and pituitary gland. The optic nerve compression was more common than parasellar type in 49 cases of Sellar meningioma. According to simpson classification standard, 33 cases had total resection and 14 cases had subtotal resection. Partial resection was performed in 2 cases, total resection rate was 67.3%. There was no significant difference in blood loss, operation time and postoperative hospitalization time between unilateral subfrontal approach and pterional approach. Conclusion: the clinical features of suprasellar meningioma and parasellar meningioma are different. The influence of the former on visual acuity, visual field, pituitary gland and optic nerve compression is more common. On the basis of preserving the nerve function and quality of life of the patients, the main objective was to remove the tumor to the maximum extent. Both unilateral subfrontal approach and pterional approach could expose the Sellar region tumor well and compare the amount of intraoperative bleeding. There was no significant difference in operation time and hospital stay.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R739.45;R730.56

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