尿白蛋白排泄率对脑梗死患者发病的影响
发布时间:2018-06-19 20:48
本文选题:尿白蛋白排泄率 + 脑梗死 ; 参考:《中国现代医学杂志》2017年29期
【摘要】:目的探讨尿白蛋白排泄率对脑梗死患者发病的影响。方法选取2013年2月-2015年7月福建医科大学附属泉州第一医院收治的脑梗死患者450例(脑梗死组)和健康者450例(对照组),比较两组入组者的尿白蛋白排泄率,对入组者的临床资料进行多因素Logistic回归分析。结果两组尿白蛋白排泄率比较,差异有统计学意义(P0.05),脑梗死组患者的尿白蛋白排泄率高于对照组。脑梗死组患者合并高血压、合并冠状动脉粥样硬化性心脏病、合并糖尿病、收缩压、低密度脂蛋白胆固醇、空腹血糖、尿白蛋白排泄率、吸烟及饮酒率与对照组比较,差异有统计学意义(P0.05)。合并高血压、合并冠状动脉粥样硬化性心脏病、合并糖尿病、低密度脂蛋白胆固醇、尿白蛋白排泄率是影响脑梗死患者发病的独立危险因素(P0.05)。结论尿白蛋白排泄率是影响脑梗死患者发病的独立危险因素,可作为预测脑梗死发生风险的重要指标之一,临床上应对高危患者进行及时干预和治疗。
[Abstract]:Objective to investigate the effect of urinary albumin excretion rate on the pathogenesis of cerebral infarction. Methods from February 2013 to July 2015, 450 patients with cerebral infarction (cerebral infarction group) and 450 healthy subjects (control group) admitted to Quanzhou first Hospital of Fujian Medical University were selected to compare the urinary albumin excretion rate between the two groups. Multivariate logistic regression analysis was used to analyze the clinical data of the patients. Results the urinary albumin excretion rate of the two groups was significantly higher than that of the control group (P 0.05), and the urinary albumin excretion rate in the cerebral infarction group was higher than that in the control group. Compared with the control group, the patients in the cerebral infarction group were complicated with hypertension, coronary atherosclerotic heart disease, diabetes mellitus, systolic blood pressure, low density lipoprotein cholesterol, fasting blood glucose, urinary albumin excretion rate, smoking and drinking rate. The difference was statistically significant (P 0.05). Hypertension, coronary atherosclerotic heart disease, diabetes mellitus, low density lipoprotein cholesterol and urinary albumin excretion rate are independent risk factors for cerebral infarction patients. Conclusion urinary albumin excretion rate is an independent risk factor for patients with cerebral infarction and can be used as an important index to predict the risk of cerebral infarction.
【作者单位】: 福建医科大学附属泉州第一医院神经内科;
【分类号】:R743.33
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