老年无症状性脑梗死患者颈动脉粥样硬化以及血清微量元素水平的改变

发布时间：2018-06-20 19:08

本文选题：老年无症状性脑梗死 + 颈动脉粥样硬化　；参考：《现代生物医学进展》2016年34期

【摘要】：目的:研究老年无症状性脑梗死患者颈动脉粥样硬化以及血清微量元素水平的改变情况。方法:选取2014年1月至2015年6月在我院体检的无症状脑梗死患者78例为观察组和健康人群78例为对照组,分析两组患者的血清中微量元素、同型半胱氨酸水平(Hcy)和颈动脉粥样硬化状况。结果:经过超声检验发现,观察组患者中发现颈动脉粥样斑块的患者41例,无斑块患者37例,对照组人群78例中发现斑块的患者为21例,无斑块患者57例。根据检测结果显示,观察组的Hcy含量高于对照组,血清中的微量元素含量Zn~(2+),Mg~(2+),Cu~(2+),Pb~(2+)的含量观察组显著低于对照组,Ca~(2+),Fe~(2+),Cr~(2+)含量显著高于对照组。差异具有显著性(P0.05)。结论:人体内锌、铜、铅、镁这几种微量元素的含量与颈动脉粥样硬化与老年无症状性脑梗死的发生率呈负相关,血清内同型半胱氨酸水平(Hcy)的含量、铁、钙、铬元素的含量与颈动脉粥样硬化与老年无症状性脑梗死发生率呈正相关。
[Abstract]:Objective: to study the changes of carotid atherosclerosis and serum trace elements in elderly patients with asymptomatic cerebral infarction. Methods: 78 patients with asymptomatic cerebral infarction who were examined in our hospital from January 2014 to June 2015 were selected as observation group and healthy group as control group. The trace elements in serum of the two groups were analyzed. Homocysteine level and carotid atherosclerosis. Results: after ultrasonic examination, 41 cases of carotid atherosclerotic plaque were found in the observation group, 37 cases were without plaque, 21 cases were found plaque and 57 cases were no plaque in the control group. The results showed that the content of Hcy in the observation group was higher than that in the control group, and the content of trace elements in the serum of the observation group was significantly lower than that of the control group. The content of the trace elements in the serum of the observation group was significantly lower than that of the control group, and the content of the observation group was significantly higher than that of the control group. The difference was significant (P 0.05). Conclusion: the contents of zinc, copper, lead and magnesium in human body are negatively correlated with the incidence of carotid atherosclerosis and asymptomatic cerebral infarction in the elderly. Chromium content was positively correlated with carotid atherosclerosis and the incidence of asymptomatic cerebral infarction in the elderly.
【作者单位】：解放军总医院第一附属医院干一科;
【基金】：全军后勤科研计划面上项目(CWS14J070)
【分类号】：R743.33

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