益气养阴活血法对2型糖尿病脑梗死患者糖代谢指标、血管内皮功能及预后的影响

发布时间：2018-06-23 17:42

本文选题：型糖尿病 + 脑梗死　；参考：《中国地方病防治杂志》2017年02期

【摘要】：目的探讨益气养阴活血法对2型糖尿病脑梗死患者糖代谢指标、血管内皮功能及预后的影响。方法选择2014年12月至2015年12月本院接诊的100例2型糖尿病合并脑梗死的患者,通过随机数表法分为观察组和对照组,各50例。给予对照组常规的治疗方式,观察组在对照组的基础上加用益气养阴活血法。观察两组治疗前后糖代谢指标、血管内皮功能、神经缺损评分、日常生活能力评分的变化,并对治疗后临床疗效比较。结果治疗后,观察组空腹血糖(FBG)、糖化血红蛋白(HbAlc)水平均低于对照组[(7.05±1.20)mmol/L比(8.43±1.56)mmol/L,(10.27±1.01)%比(11.68±2.54)%],血管内皮细胞生长因子(VEGF)水平高于对照组[(184.24±17.91)ng/L比(153.23±15.86)ng/L],神经功能缺损评分低于对照组,日常生活能力评分高于对照组[(8.34±1.42)比(15.76±3.18),(85.46±7.81)比(73.13±6.43)],治疗后总有效率比对照组高[82.0%(41/50)比98.0%(49/50)],差异均具有统计学意义(P0.05)。结论在2型糖尿病脑梗死患者中使用益气养阴活血法可有效改善患者血糖水平、血管内皮功能及日常生活能力,提高预后,效果显著,值得在临床上应用推广。
[Abstract]:Objective to investigate the effects of supplementing qi and nourishing yin and activating blood circulation on glucose metabolism, vascular endothelial function and prognosis in type 2 diabetic patients with cerebral infarction. Methods 100 patients with type 2 diabetes complicated with cerebral infarction from December 2014 to December 2015 were randomly divided into observation group (n = 50) and control group (n = 50). The control group was given routine treatment, and the observation group was treated with the method of nourishing qi, nourishing yin and activating blood circulation on the basis of control group. The changes of glucose metabolism index, vascular endothelial function, nerve defect score and activity of daily living score were observed before and after treatment, and the clinical efficacy was compared. Results after treatment, the levels of fasting blood glucose (FBG) and glycosylated hemoglobin (HbAlc) in the observation group were lower than those in the control group [(7.05 卤1.20) mmol / L, (8.43 卤1.56) mmol / L, (10.27 卤1.01)% vs (11.68 卤2.54)%], and the levels of vascular endothelial growth factor were higher than those in the control group [(184.24 卤17.91) ng / L vs (153.23 卤15.86) ng / L]. The score of ADL was higher than that of the control group [(8.34 卤1.42) vs (15.76 卤3.18), () 85.46 卤7.81], and the total effective rate after treatment was higher than that of the control group [82.0% (41 / 50) vs 98.0% (49 / 50)]. The difference was statistically significant (P0.05). Conclusion the method of nourishing qi, nourishing yin and activating blood circulation can effectively improve the blood sugar level, vascular endothelial function and daily living ability in patients with type 2 diabetes mellitus cerebral infarction, and improve the prognosis. It is worth popularizing in clinic.
【作者单位】：沂南县人民医院;
【基金】：山东省中医药科技发展计划项目(2013104)
【分类号】：R587.2;R743.33

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