探讨高血压及合并冠心病或脑梗塞患者的动态血压特点

发布时间：2018-07-01 16:00

本文选题：高血压 + 冠心病　；参考：《山东大学》2014年硕士论文

【摘要】：目的：观察单纯高血压及高血压合并冠心病患者、高血压合并脑梗塞患者的动态血压特点,并分析掌握其规律,以指导降压治疗。方法：对47例冠心病合并高血压患者(A组)、50例脑梗塞合并高血压患者(B组)及46例单纯高血压患者(C组)行24小时动态血压监测。结果：A、B组患者24小时平均收缩压(24hMSBP)、24小时平均脉压(24hMPP)、夜间平均收缩压(nMSBP)均高于C组患者(P0.05),较后者,前两组患者存在更高的血压节律异常及晨峰现象(P0.05)。B组患者24hMSBP、24hMPP高于A组患者(P0.05),A组患者24小时平均舒张压(24hMDBP)高于B组患者(P0.05)。A组患者血压晨峰发生率高于B组患者(P0.05),两组患者血压昼夜节律比较无统计学差异(P0.05)。结论：血压持续升高、脉压增大、血压昼夜节律消失及血压晨峰现象是高血压患者发生冠心病及脑梗塞的重要危险因素；冠心病患者更多存在血压晨峰；脑梗塞组患者收缩压较冠心病组患者高,冠心病组患者舒张压较脑梗塞组患者高。
[Abstract]:Aim: to observe the characteristics of ambulatory blood pressure (ABBP) in patients with hypertension and coronary heart disease (CHD) and hypertensive patients with cerebral infarction (CI), and to analyze and master the rules of ABP in order to guide hypotensive therapy. Methods: 24 hours ambulatory blood pressure monitoring was performed in 47 patients with coronary heart disease complicated with hypertension (group A), 50 patients with cerebral infarction with hypertension (group B) and 46 patients with simple hypertension (group C). Results 24 hours mean systolic pressure (24 h MSBP) and 24 hour mean pulse pressure (24 h MPP) in group B were higher than those in group C (P 0.05), and the mean systolic pressure at night (nMSBP) in group B were higher than those in group C (P0.05). There were higher blood pressure rhythm abnormality and morning peak phenomenon in the first two groups (P0.05). The 24 h MSBP 24h MPP in group B was higher than that in group A (P0.05). The mean 24-hour diastolic blood pressure (24 h MDBP) in group A was higher than that in group B (P0.05). The incidence of morning peak in group A was higher than that in group B (P0.05), and the incidence of morning peak in group A was higher than that in group B (P0.05). There was no significant difference in circadian rhythm of blood pressure between the two groups (P0.05). Conclusion: continuous increase of blood pressure, increase of pulse pressure, disappearance of circadian rhythm of blood pressure and morning peak of blood pressure are important risk factors for coronary heart disease and cerebral infarction in patients with hypertension, and there are more morning peaks of blood pressure in patients with coronary heart disease. Systolic blood pressure in cerebral infarction group was higher than that in coronary heart disease group, and diastolic blood pressure in coronary heart disease group was higher than that in cerebral infarction group.
【学位授予单位】：山东大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R544.1;R541.4;R743.3

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