aSAH患者诱发继发性癫痫的危险因素分析

发布时间：2018-07-21 21:09

【摘要】：目的探讨动脉瘤性蛛网膜下腔出血(a SAH)患者继发性癫痫的危险因素。方法对2009年3月~2015年5月在我院神经外科行显微手术夹闭的162例a SAH患者的临床资料进行回顾性分析,将继发性癫痫分为早期癫痫和晚期癫痫,分析a SAH患者继发早、晚期癫痫的危险因素,包括年龄、性别、原发性高血压病史、起病时意识障碍持续时间、入院时格拉斯哥昏迷评分(GCS)、Fisher分型、责任动脉瘤的部位、脑血管痉挛、脑积水、动脉瘤再破裂以及格拉斯哥预后分级(GOS)。结果 162例a SAH患者中,早期癫痫14例,晚期癫痫18例。原发性高血压病史为发生早期癫痫的危险因素(P0.05);脑积水和动脉瘤再破裂为发生晚期癫痫的危险因素(P0.05)。结论原发性高血压病史可能是a SAH继发早期癫痫的危险因素,而脑积水和动脉瘤再破裂则可能是继发晚期癫痫的危险因素。
[Abstract]:Objective to investigate the risk factors of secondary epilepsy in patients with aneurysmal subarachnoid hemorrhage (a SAH). Methods the clinical data of 162 a SAH patients with microsurgical clipping in Department of Neurosurgery, our hospital, March 2009, in May ~2015, were retrospectively analyzed. Secondary epilepsy was divided into early epilepsy and late epilepsy, and the secondary epilepsy of a SAH patients was analyzed. The risk factors of advanced epilepsy include age, sex, history of primary hypertension, duration of awareness disorder at onset, Glasgow coma score (GCS), Fisher classification, location of the responsible aneurysm, cerebral vasospasm, hydrocephalus, aneurysm re rupture and Glasgow prognostic classification (GOS). Results 162 cases of a SAH were in the early stage. 14 cases of epilepsy and 18 cases of advanced epilepsy. The history of primary hypertension is a risk factor for early epilepsy (P0.05); hydrocephalus and aneurysm re rupture are risk factors for late epilepsy (P0.05). Conclusion the history of primary hypertension may be a risk factor for early epilepsy secondary to a SAH, while hydrocephalus and aneurysm re rupture may be the following Risk factors for late onset epilepsy.
【作者单位】：浙江省舟山市普陀区人民医院神经精神科;
【基金】：浙江省中医药科学研究基金(2014ZSZX12)
【分类号】：R743.35

【相似文献】