颅内动脉瘤破裂危险因素分析

发布时间：2018-07-24 19:19

【摘要】：目的探讨颅内动脉瘤破裂的危险因素。方法回顾分析2011年1月~2016年1月在我院确诊为颅内动脉瘤的373例患者的病历资料,根据动脉瘤破裂与否将研究对象分为破裂组(n=343)和未破裂组(n=30),对两组患者的临床资料及动脉瘤相关特征资料进行搜集,并进行单因素分析筛选,然后行Logistic回归分析。结果(1)经χ2分析及t检验示年龄、吸烟、饮酒、动脉瘤直径、动脉瘤部位等比较结果具有统计学意义(P0.05)。(2)经logistic回归分析示颅内动脉瘤发生破裂的相关危险因素有青年(OR=1.437,95%CI=0.542~3.813)、老年(OR=1.083,95%CI=0.619~1.895)、中等动脉瘤(OR=1.764,95%CI=0.611~5.096)、前交通动脉瘤(OR=2.839,95%CI=1.238~6.509)、后交通动脉瘤(OR=1.102,95%CI=0.624~1.944)、高血压(OR=1.04895%CI=0.585~1.877)、饮酒史(OR=1.286,95%CI=0.503~3.290)。结论青年、老年、高血压、饮酒史、中等动脉瘤、前交通动脉瘤、后交通动脉瘤是颅内动脉瘤破裂的相关危险因素。
[Abstract]:Objective to investigate the risk factors of intracranial aneurysm rupture. Methods a retrospective analysis of 373 cases of intracranial aneurysm in our hospital in January ~2016 January 2011 was reviewed. According to the ruptured aneurysm rupture or not, the subjects were divided into rupture group (n=343) and unruptured group (n=30), and the clinical data and aneurysm related characteristics of the two groups were funded. The material was collected and screened by single factor analysis, and then Logistic regression analysis was performed. Results (1) the results of smoking, drinking, aneurysm diameter and aneurysm location were statistically significant (P0.05) by x 2 Analysis and t test (P0.05). (2) the risk factors of intracranial aneurysm rupture were analyzed by logistic regression (OR=1. 437,95%CI=0.542~3.813), old age (OR=1.083,95%CI=0.619~1.895), middle aneurysm (OR=1.764,95%CI=0.611~5.096), anterior communicating artery aneurysm (OR=2.839,95%CI=1.238~6.509), posterior communicating artery aneurysm (OR=1.102,95%CI=0.624~1.944), hypertension (OR=1.04895%CI=0.585 ~1.877), drinking history (OR=1.286,95%CI=0.503~3.290). Conclusion young, old, high blood. Pressure, history of drinking, moderate aneurysms, anterior communicating artery aneurysms and posterior communicating artery aneurysms are risk factors for ruptured intracranial aneurysms.
【作者单位】：湖南省人民医院神经内科;
【基金】：湖南省科技厅资助项目(No.2013FJ3119)
【分类号】：R743

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