中性粒细胞与淋巴细胞比值对脑卒中相关性肺炎的预测价值
发布时间:2018-08-04 19:30
【摘要】:目的探讨血清中性粒细胞与淋巴细胞比值(NLR)对高血压病性脑出血患者发生卒中相关性肺炎(SAP)的预测价值。方法采用回顾性研究方法,选取2015年1月-2016年11月南华大学附属南华医院重症医学科收治的年龄在50~80岁,且住院时间≥7 d的118例高血压病性脑出血患者。根据患者入院后7 d是否发生SAP将所有患者分为SAP组及非SAP组。比较两组患者的一般临床信息,分析入院时APACHEⅡ评分与入院后第1、3及5天的NLR值及白细胞(WBC)值的相关性,并评价两组患者在入院后第1、3及5天的WBC及NLR的变化以及组间差异,绘制受试者工作特征曲线(ROC曲线),评价不同时间各个指标对SAP发生的预测价值。结果入院时APACHEⅡ评分与入院后第3、5天的NLR水平第3天(r=0.360,P=0.000);第5天(r=0.390,P=0.000)及WBC水平第3天(r=0.220,P=0.015);第5天(r=0.200,P=0.031)呈正相关。SAP患者在入院后的第1、3及5天的NLR值分别为(10.89±3.05)、(12.42±3.75)及(9.28±3.31)。其中,第3天的NLR值达到最高峰。且在第3、5天中,SAP组的WBC与NLR值均大于同期的非SAP组(P0.05)。入院后第3、5天的NLR及WBC均能很好地预测SAP(P0.05),2个时间的预测价值差异无统计学意义。且NLR的曲线下面积(AUC)(第3天为0.943,第5天为0.924)大于同期WBC的AUC值(第3天为0.823,第5天为0.809)。将NLR与WBC联合后不能增加曲线下面积。结论入院后第3、5天的NLR值对于评估SAP在临床上有很好的预测价值。
[Abstract]:Objective to investigate the predictive value of serum neutrophil / lymphocyte ratio (NLR) in patients with stroke associated pneumonia (SAP) in hypertensive intracerebral hemorrhage (hypertensive intracerebral hemorrhage). Methods A retrospective study was conducted on 118 patients with hypertensive intracerebral hemorrhage who were admitted to the Department of intensive Medicine of the South China Hospital affiliated to South China University from January 2015 to November 2016, aged 50 to 80 years and hospitalized for more than 7 days. All patients were divided into SAP group and non-SAP group according to whether SAP occurred 7 days after admission. To compare the general clinical information of the two groups, to analyze the correlation between the APACHE 鈪,
本文编号:2164914
[Abstract]:Objective to investigate the predictive value of serum neutrophil / lymphocyte ratio (NLR) in patients with stroke associated pneumonia (SAP) in hypertensive intracerebral hemorrhage (hypertensive intracerebral hemorrhage). Methods A retrospective study was conducted on 118 patients with hypertensive intracerebral hemorrhage who were admitted to the Department of intensive Medicine of the South China Hospital affiliated to South China University from January 2015 to November 2016, aged 50 to 80 years and hospitalized for more than 7 days. All patients were divided into SAP group and non-SAP group according to whether SAP occurred 7 days after admission. To compare the general clinical information of the two groups, to analyze the correlation between the APACHE 鈪,
本文编号:2164914
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