120例复发性脑卒中患者复发危险因素分析

发布时间：2018-08-06 16:42

【摘要】：目的对脑卒中患者复发危险因素进行研究,为脑卒中的预防提供思路。方法选取2015年1月至2016年12月在郑州大学第一附属医院就诊复发性脑卒中患者120例作为本研究观察组(复发组),以同期就诊的120例初发性脑卒中患者作为对照组(初发组)。采取1:1病例对照设计,按照纳入排除标准,选择研究对象。根据住院登记记录复发组与未复发组的相关资料,包括:性别、年龄、吸烟、糖尿病、高血压、卒中家族史等信息,应用卡方检验和多因素Logistic回归进行统计分析。结果单因素采用卡方检验显示性别x~2=0.067,P0.05;年龄x~2=6.168,P0.05;家族史x~2=7.200,P0.05;抑郁x~2=4.941,P0.05;抽烟x~2=6.602,P0.05;高血压x~2=5.567,P0.05;糖尿病x~2=0.287,P0.05,说明年龄、抑郁、高血压、吸烟、卒中家族史是缺血性脑卒中复发的危险因素;多因素分析显示抑郁、高血压、卒中家族使OR值(95%CI)分别为0.473(0.279-0.813),2.410(1.275-4.449),2.204(1.233-3.978)均P0.05,说明抑郁、高血压、卒中家族史是缺血性脑卒中复发的独立危险因素。结论1.通过本研究发现年龄抑郁、高血压、卒中家族史是缺血性脑卒中复发的独立危险因素。2.年龄、抑郁、高血压、卒中家族史、吸烟是缺血性脑卒中复发的相关危险因素。
[Abstract]:Objective to study the risk factors of stroke recurrence in order to provide ideas for the prevention of stroke. Methods from January 2015 to December 2016, 120 patients with recurrent stroke in the first affiliated Hospital of Zhengzhou University were selected as the observation group (relapse group) and 120 patients with primary stroke as the control group (primary group). The 1:1 case-control design was adopted and the subjects were selected according to the exclusion criteria. According to the data of the recurrent group and the non-recurrent group, including sex, age, smoking, diabetes, hypertension, family history of stroke and so on, chi-square test and multivariate Logistic regression were used for statistical analysis. Results the univariate chi-square test showed that the sex of the patients was: sex (x) 0.067 (P 0.05); age (x = 26.168) (P 0.05); family history (x = 27.200) (P 0.05); depression (x = 24.941) (P 0.05); smoking (x = 26.602) (P 0.05); hypertension (x = 25.567) (P 0.05); diabetes mellitus (x = 20.28 7) P 0.05, indicating that age, depression, hypertension, smoking and stroke were the risk factors for recurrence of ischemic stroke. Multivariate analysis showed that the OR values (95%CI) of depression, hypertension and stroke family were 0.473 (0.279-0.813) and 2.410 (1.275-4.449) and 2.204 (1.233-3.978), respectively (P 0.05), which indicated that depression, hypertension and family history of stroke were independent risk factors for recurrence of ischemic stroke. Conclusion 1. In this study, we found that age depression, hypertension and family history of stroke were independent risk factors of ischemic stroke recurrence. Age, depression, hypertension, family history of stroke, and smoking are risk factors for recurrence of ischemic stroke.
【学位授予单位】：郑州大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R743.3

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