尤瑞克林联合降纤酶对ACI患者的神经功能缺损及Fg的影响

发布时间：2018-08-09 10:18

【摘要】：目的探讨尤瑞克林联合降纤酶对急性脑梗塞患者神经功能缺损及血浆纤维蛋白原的影响。方法选取我院2014年3月～2016年9月急性脑梗塞患者67例,随机分组,对照组33例,观察组34例,对照组予以尤瑞克林治疗,观察组实施尤瑞克林联合降纤酶治疗,观察比较两组治疗前后神经功能缺损(NIHSS)评分、血浆纤维蛋白原水平,并统计两组临床疗效及不良反应发生率。结果观察组总有效率为94.12%,高于对照组72.73%,差异具有统计学意义(P0.05);治疗后1周、2周、1个月观察组NIHSS评分及血浆纤维蛋白原水平均低于对照组,差异具有统计学意义(P0.05);两组不良反应发生率比较,差异无统计学意义(P0.05)。结论对急性脑梗塞患者给予尤瑞克林联合降纤酶治疗,疗效显著,可有效改善患者血浆纤维蛋白原水平及神经功能缺损程度,安全性高。
[Abstract]:Objective to investigate the effects of eurexine combined with defibrase on neurologic impairment and plasma fibrinogen in patients with acute cerebral infarction. Methods Sixty-seven patients with acute cerebral infarction from March 2014 to September 2016 were randomly divided into control group (n = 33), observation group (n = 34) and control group (n = 34). The (NIHSS) score and plasma fibrinogen level before and after treatment were observed and compared between the two groups. Results the total effective rate in the observation group was 94.12, which was higher than that in the control group (P 0.05), and the NIHSS score and plasma fibrinogen level in the observation group were lower than those in the control group at 1 week and 1 month after treatment (P0.05). The difference was statistically significant (P0.05), the incidence of adverse reactions between the two groups, the difference was not statistically significant (P0.05). Conclusion Eucrine combined with defibrase is effective in improving plasma fibrinogen level and nerve function defect in patients with acute cerebral infarction.
【学位授予单位】：郑州大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R743.3

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