ABCD2评分与短暂性脑缺血发作患者15d内预后的关系

发布时间：2018-10-05 18:16

【摘要】：目的探讨ABCD2评分与短暂性脑缺血发作(TIA)15 d内预后的关系。方法选择TIA患者224例。以住院15 d为观察终点,期间进展为完全性脑梗死患者75例为进展组,未进展为完全性脑梗死患者149例为未进展组。采用自行设计TIA调查表进行调查,采用ABCD2评分系统对全部TIA患者进行评估。结果 (1)ABCD2评分系统中,有糖尿病史的TIA患者进展为脑梗死的危险是无糖尿病者的2.585倍(OR=2.585,95%CI:1.457~4.588);随着TIA持续时间增加,TIA患者进展为脑梗死的比例增加(χ~2=52.847,P=0.000);随着临床特征加重,TIA患者进展为脑梗死的比例增加(χ~2=42.535,P=0.000)。(2)随着ABCD2评分的增加,TIA患者进展为脑梗死的比例增加(χ~2=118.601,P=0.000);ABCD2评分危险分层与TIA患者预后的关系中,低危患者没有进展为脑梗死,中危患者进展为脑梗死的比例为22.5%,高危患者进展为脑梗死的比例为88.1%,差异有统计学意义(χ~2=107.600,P=0.000)。结论 ABCD2评分增加与TIA患者15 d内进展为脑梗死密切相关,ABCD2评分危险分层为中、高危TIA患者为临床重点干预人群。
[Abstract]:Objective to investigate the relationship between ABCD2 score and prognosis of transient ischemic attack (TIA) within 15 days. Methods 224 patients with TIA were selected. After 15 days of hospitalization, 75 patients with complete cerebral infarction and 149 patients with incomplete cerebral infarction were observed as progression group. A self-designed TIA questionnaire was used to evaluate all TIA patients. Results (1) in the ABCD2 scoring system, The risk of progression to cerebral infarction in TIA patients with history of diabetes was 2.585 times higher than that in patients without diabetes mellitus (OR=2.585,95%CI:1.457~4.588), and the proportion of patients with TIA progression to cerebral infarction increased with the duration of TIA (蠂 ~ 2 / 2, 52.847, P ~ (0.000), and with the exacerbation of clinical features, the rate of progression to cerebral infarction was higher in patients with TIA than in patients without diabetes mellitus (P ~ (0.000). With the increase of ABCD2 score, the proportion of patients with progressive cerebral infarction (蠂 2 / 2) increased (蠂 2 / 118.601 / 0. 000) and the risk stratification of ABCD2 score was associated with the prognosis of TIA patients. The proportion of middle risk patients with cerebral infarction was 22.50.The proportion of high-risk patients with cerebral infarction was 88.1.The difference was statistically significant (蠂 2 107.600 P 0.000). Conclusion the increase of ABCD2 score is closely related to the progression of cerebral infarction in patients with TIA within 15 days. The risk stratification of ABCD2 score is middle, and the high risk TIA patients are the key intervention population.
【作者单位】：襄阳市谷城县人民医院神经内科;湖北文理学院医学院;
【基金】：湖北文理学院与谷城县人民医院横向合作课题(HY2013112)
【分类号】：R743.31

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