CEUS颈动脉斑块灌注模式与短暂性脑缺血发作患者脑卒中发病的关系

发布时间：2018-10-16 11:40

【摘要】：目的探讨短暂性脑缺血发作(TIA)患者颈动脉斑块CEUS的增强模式及与发生缺血性脑卒中及再发TIA的相关性。方法对符合纳入标准的73例患者行颈动脉常规超声检查,选择颈总动脉分叉处及颈内动脉起始段斑块厚度2.5mm的61例患者进行CEUS检查,随访至少18个月,并将患者分为再发病组与未再发病组。患者18个月内发生缺血性脑卒中或再发TIA的危险因素采用Logistic回归分析。结果两组高血压、糖尿病、高血脂、吸烟史、脑卒中家族史、服药依从性、二维超声及CEUS特征差异均有统计学意义(P均0.05)。多变量Logistic回归分析显示,影响再发病的因素按强度大小排列,分别为CEUS特征、高血压、药物依从性、高血糖及二维超声特征。结论 CEUS可对颈动脉斑块内新生血管的灌注模式进行评估,并对TIA患者发生缺血性脑卒中或再发TIA进行预测,对指导临床进行针对性预防有重要价值。
[Abstract]:Objective to investigate the enhanced pattern of carotid plaque CEUS in patients with transient ischemic attack (TIA) and its correlation with ischemic stroke and recurrent TIA. Methods Sixty-one patients with carotid artery bifurcation and internal carotid artery plaque thickness (2.5mm) were examined by CEUS in 73 patients who met the inclusion criteria, and were followed up for at least 18 months. The patients were divided into recurrent group and non-recurrent group. The risk factors of ischemic stroke or recurrent TIA within 18 months were analyzed by Logistic regression analysis. Results there were significant differences in hypertension, diabetes, hyperlipidemia, smoking history, family history of stroke, drug compliance, two-dimensional ultrasound and CEUS between the two groups (P 0.05). Multivariate Logistic regression analysis showed that the factors affecting recurrence were CEUS characteristics, hypertension, drug compliance, hyperglycemia and two-dimensional ultrasound. Conclusion CEUS can evaluate the perfusion pattern of neovascularization in carotid plaque and predict the occurrence of ischemic stroke or recurrence of TIA in patients with TIA.
【作者单位】：深圳市第二人民医院超声科;深圳市第二人民医院神经内科;
【基金】：深圳市科技计划项目(JCYJ20140414170821323)
【分类号】：R743.3

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