黄芪注射液治疗缺血性脑卒中偏瘫的效果

发布时间：2018-10-18 13:28

【摘要】：目的探讨黄芪注射液治疗缺血性脑卒中偏瘫的临床效果及对血脂和骨密度的影响。方法 2014年1月~2015年6月116例缺血性脑卒中偏瘫患者随机分为对照组(n=54)和观察组(n=62)。对照组常规治疗基础上给予针灸治疗,观察组在对照组基础上联合给予黄芪注射液治疗。采用美国国立卫生研究院卒中量表(NIHSS)及日常生活能力量表(ADL)进行评价,观察临床疗效,测量血脂水平及骨密度。结果治疗后,与对照组比较,观察组的治疗总有效率提高(χ~2=3.960,P0.05);NIHSS评分明显降低(t=3.490,P=0.001),ADL评分明显升高(t=2.820,P=0.006);总胆固醇、三酰甘油、低密度脂蛋白胆固醇水平显著降低(t4.190,P0.001),而高密度脂蛋白胆固醇无变化(P0.05);偏瘫侧前臂、偏瘫侧股骨、偏瘫侧Ward区骨密度均升高(t2.060,P0.05)。结论黄芪注射液能够提高临床疗效,减轻神经功能缺损,提高患者日常生活能力,并能改善血脂,增加偏瘫侧骨密度。
[Abstract]:Objective to investigate the clinical effect of astragalus injection on ischemic stroke hemiplegia and its effect on blood lipid and bone mineral density. Methods from January 2014 to June 2015, 116 patients with ischemic stroke hemiplegia were randomly divided into control group (n = 54) and observation group (n = 62). The control group was treated with acupuncture and moxibustion on the basis of routine treatment, and the observation group was treated with astragalus injection on the basis of the control group. The stroke scale (NIHSS) and the activity of daily living (ADL) were used to evaluate the clinical efficacy, blood lipids and bone mineral density (BMD). Results after treatment, compared with the control group, the total effective rate of the observation group was significantly increased (蠂 ~ 2 + 3.960g / P 0.05); NIHSS score was significantly lower (t = 3.490) P ~ (0.001), ADL score was significantly higher (t ~ (2.820) P ~ (0.006), total cholesterol, triglyceride, total cholesterol, triglyceride, The low density lipoprotein cholesterol (LDL-C) level was significantly decreased (t4.190,P0.001), while HDL-C did not change (P0.05), while the bone mineral density (BMD) in the forearm, femur and Ward area of hemiplegic side were all increased (P0.05). Conclusion Astragalus injection can improve the clinical curative effect, relieve the nerve function defect, improve the daily life ability of the patients, improve blood lipid and increase the bone mineral density of the hemiplegic side.
【作者单位】：重庆三峡医药高等专科学校;重庆三峡医药高等专科学校附属医院;湖南中医药大学;
【基金】：教育部国家级重点学科基金项目(No.WBZ2013-11)
【分类号】：R743.3

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