在NF2中Merlin蛋白与Hippo信号通路的相互作用
发布时间:2018-10-29 20:47
【摘要】:正多发性神经纤维瘤病(neurofibromatosis,NF),根据其临床及遗传学特征分为1型和2型。1930年,Gardner和Frazier证实神经纤维瘤病Ⅱ型(neurofibromatosis type 2,NF2)为常染色体显性遗传性疾病,临床上通常把NF2分为Wishart型和Gardner型2个亚型。近年来,随着分子生物学和细胞生物学技术的广泛应用,已证实位于第22号染色体长臂上的NF2肿瘤抑制
[Abstract]:Multiple neurofibromatosis (neurofibromatosis,NF) is classified into type 1 and type 2 according to its clinical and genetic characteristics. In 1930, Gardner and Frazier confirmed that neurofibromatosis type 鈪,
本文编号:2298780
[Abstract]:Multiple neurofibromatosis (neurofibromatosis,NF) is classified into type 1 and type 2 according to its clinical and genetic characteristics. In 1930, Gardner and Frazier confirmed that neurofibromatosis type 鈪,
本文编号:2298780
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