红花黄色素联合依达拉奉治疗128例急性脑梗死的效果分析

发布时间：2018-11-14 08:06

【摘要】：目的观察红花黄色素联合依达拉奉治疗脑梗死的效果。方法选择2014年1月至2016年1月于我院就诊的急性脑梗塞患者256例,按照随机数字法将患者分为研究组和对照组,各128例。对照组在常规治疗的基础上加用依达拉奉治疗,研究组在对照组的基础上加用红花黄色素治疗。观察两组治疗前后的NIHSS评分和炎症因子变化,以及治疗效果。结果两组治疗前NIHSS评分均无统计学意义(P0.05);治疗后两组较治疗前均有降低,且研究组下降程度高于对照组,差异有统计学意义(P0.05)。治疗前两组hs-CRP、IL-2、IL-8和TNF-α等水平差异无统计学意义(P0.05),治疗后两组均有明显降低,且研究组比对照组下降更明显,差异有统计学意义(P0.05)。研究组治疗有效率为95.31%,高于对照组的83.59%,差异有统计学意义(P0.05)。结论红花黄色素联合依达拉奉治疗急性脑梗塞治疗效果显著,可改善患者预后,且安全可靠。
[Abstract]:Objective to observe the effect of safflower yellow and Edaravone on cerebral infarction. Methods 256 patients with acute cerebral infarction from January 2014 to January 2016 were randomly divided into two groups: study group and control group. The control group was treated with Edaravone on the basis of routine treatment, while the study group was treated with safflower yellow pigment on the basis of the control group. The changes of NIHSS score, inflammatory factor and therapeutic effect were observed before and after treatment. Results there was no significant difference in NIHSS score between the two groups before treatment (P0.05); after treatment, the NIHSS scores in the two groups were lower than before, and the degree of decrease in the study group was higher than that in the control group, the difference was statistically significant (P0.05). There was no significant difference in the levels of hs-CRP,IL-2,IL-8 and TNF- 伪 between the two groups before treatment (P0.05). After treatment, the levels of hs-CRP,IL-2,IL-8 and TNF- 伪 in the two groups were significantly decreased, and the decrease in the study group was more obvious than that in the control group (P0.05). The effective rate of treatment in the study group was 95.31, higher than that in the control group (83.59), the difference was statistically significant (P0.05). Conclusion the combination of safflower yellow and Edaravone is effective in the treatment of acute cerebral infarction. It can improve the prognosis of patients and is safe and reliable.
【作者单位】：江苏省海门市人民医院;
【分类号】：R743.33

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