眼震电图和前庭诱发肌源电位在眩晕诊断的应用分析

发布时间：2018-11-14 13:32

【摘要】：目的：研究眩晕患者的眼震视图（VNG）及前庭诱发肌源电位（VEMP）的特性，通过与健康对照组的相应检测数据的对比，探讨VNG和VEMP在眩晕疾病中的诊断价值。研究对象及方法：对32例健康对照按不同的性别、年龄分布进行VEMP、VNG检测。对114例眩晕患者按眩晕的临床表现分为真性眩晕和假性眩晕组进行VNG、VEMP检查，将其检测数据与健康对照进行对比，分析比较不同组别之间各项数据的差异。结果：1．健康对照组不同性别、年龄组的VEMP单侧耳P13、N23潜伏期，及双耳耳间潜伏期差、耳间振幅差（IAD）、耳间不对称率差异无统计学意义，P0.05；男性的VEMP振幅高于女性，组间差异有统计学意义，P0.05。不同性别间温度试验异常率差异无统计学意义，P0.05；老年组的温度试验异常率高于中年组，组间差异有统计学意义，P0.05。 2．真性眩晕的VEMP各波潜伏期较健康对照组延长，差异有统计学意义，P0.05。真性眩晕组VNG异常检出率高于健康对照组，差异有统计学意义，P0.05。真性眩晕组的VEMP异常检出率、VNG异常检出率和IAD、耳间不对称率差异无统计学意义，，P0.05。3．假性眩晕组的VEMP单侧耳P13、N23潜伏期、VNG异常检出率均高于健康对照组，组间差异有统计学意义，P0.05；假性眩晕组的VEMP异常检出率与VNG异常检出率差异无统计学意义，P0.05；假性眩晕组的双耳耳间潜伏期差、IAD、耳间不对称率差异无统计学意义，P0.05。4．真性眩晕的VEMP异常检出率较假性眩晕增高，组间差异有统计学意义，P0.05。真性眩晕组的VNG异常检出率与假性眩晕对比差异无统计学意义，P0.05。结论：1.VNG和VEMP联合应用可作为眩晕鉴别诊断的辅助工具。2.VEMP在真性眩晕的诊断中有更高的敏感性。3.VNG可区分前庭周围性和中枢性病变。4.VNG中的温度试验、位置试验对于判断半规管病变有特殊的意义。
[Abstract]:Objective: to study the characteristics of nystagmus view (VNG) and vestibular evoked myogenic potential (VEMP) in patients with vertigo, and to explore the diagnostic value of VNG and VEMP in vertigo by comparing with the corresponding data of healthy control group. Methods: VEMP,VNG was performed on 32 healthy controls according to different sex and age distribution. According to the clinical manifestation of vertigo, 114 cases of vertigo were divided into true vertigo group and false vertigo group by VNG,VEMP examination. The data were compared with the healthy control group, and the differences between different groups were analyzed. Results: 1. There was no significant difference in the latency of VEMP single lateral ear P13N23, the difference of interauricular latency and amplitude difference between (IAD), ears in healthy control group (P 0.05). The VEMP amplitude of male was higher than that of female, and the difference between groups was statistically significant (P 0.05). The abnormal rate of temperature test in the old group was higher than that in the middle age group, and the difference between the two groups was statistically significant (P 0.05). 2. The latency of VEMP waves in true vertigo group was longer than that in healthy control group (P 0.05). The positive rate of VNG abnormality in true vertigo group was higher than that in healthy control group (P 0.05). There was no significant difference in the detection rate of VEMP abnormality, VNG abnormality and asymmetry rate between IAD, ears in true vertigo group (P0.05.3). The latent period and VNG abnormality detection rate of VEMP single lateral ear in pseudo vertigo group were higher than those in healthy control group. The difference between groups was statistically significant (P0.05; There was no significant difference between VEMP abnormality and VNG abnormality in pseudo vertigo group (P 0.05). There was no significant difference in latency between ears and asymmetry rate of IAD, in false vertigo group (P0.05.4). The detection rate of VEMP abnormality in veritable vertigo group was higher than that in false vertigo group, and the difference between groups was statistically significant (P0.05). There was no significant difference in VNG abnormal detection rate between true vertigo group and false vertigo group (P 0.05). Conclusion: the combination of 1.VNG and VEMP can be used as an assistant tool for differential diagnosis of vertigo. 2.VEMP is more sensitive in the diagnosis of true vertigo. 3.VNG can distinguish vestibular peripheral and central lesions. Location test is of special significance for the diagnosis of semicircular canal lesions.
【学位授予单位】：福建医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R742

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