脑卒中患者医院感染病原菌分布及经济损失分析

发布时间：2018-11-25 21:47

【摘要】：目的调查脑卒中患者医院感染病原菌分布及经济损失情况,为临床防治措施的制定提供理论依据。方法回顾性分析2013年1月-2015年12月医院收治的296例脑卒中患者的各项临床资料,将发生医院感染的66例患者分为感染组,未发生医院感染的230例患者分为未感染组;分析感染组患者感染部位和病原菌分布,同时分别对比两组患者2013-2015年度的住院费用。结果感染组66例患者共发生医院感染71例次,其中下呼吸道感染最常见,占49.30%,其次为上呼吸道感染,占22.54%;共分离出病原菌71株,其中革兰阴性菌48株占67.61%,革兰阳性菌20株占28.17%,真菌3株占4.23%;革兰阴性菌中铜绿假单胞菌最常见,占52.08%;革兰阳性菌中金黄色葡萄球菌最常见,占40.00%;感染组2013年住院费用(14697.51±2221.56)元、2014年(14018.95±2634.78)元、2015年(13997.58±2467.48)元,均显著高于未感染组(P0.05)。结论革兰阴性菌是脑卒中患者医院感染的主要致病菌,医院感染的发生可显著增加脑卒中患者的住院费用;临床应加强医院感染的预防控制,有效降低患者的医疗支出。
[Abstract]:Objective to investigate the distribution and economic loss of nosocomial infection in stroke patients and to provide theoretical basis for clinical prevention and treatment. Methods the clinical data of 296 stroke patients admitted to hospital from January 2013 to December 2015 were retrospectively analyzed. 66 patients with nosocomial infection were divided into infection group and 230 patients without nosocomial infection were divided into uninfected group. The location of infection and the distribution of pathogens in the infected group were analyzed, and the hospitalization expenses of the two groups in 2013-2015 were compared. Results there were 71 nosocomial infections in 66 patients in the infection group, among which the lower respiratory tract infection was the most common (49.30%), followed by the upper respiratory tract infection (22.54%). A total of 71 strains of pathogenic bacteria were isolated, of which 48 were Gram-negative bacteria (67.61), 20 Gram-positive bacteria (28.17), and 3 fungi (4.23%), among which gram-negative bacteria were the most common (52.08%). Among Gram-positive bacteria, Staphylococcus aureus was the most common, accounting for 40.00m. The cost of hospitalization in the infection group was (14697.51 卤2221.56) yuan in 2013, (14018.95 卤2634.78) yuan in 2014 and (13997.58 卤2467.48) yuan in 2015, which was significantly higher than that in the non-infected group (P0.05). Conclusion Gram-negative bacteria are the main pathogens of nosocomial infection in stroke patients, and the incidence of nosocomial infection can significantly increase the hospitalization cost of stroke patients, and the prevention and control of nosocomial infection should be strengthened in clinic to effectively reduce the medical expenses of patients.
【作者单位】：平顶山市第二人民医院神经内一科;
【基金】：河南省科技厅一般资助项目(20139087343)
【分类号】：R743.3

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