抗Ma2抗体相关脑炎7例报告
发布时间:2018-12-26 06:39
【摘要】:正抗Ma2(即副肿瘤相关神经肿瘤抗原的一种)抗体相关脑炎是一种抗细胞内抗原抗体相关的自身免疫性脑炎,除认知功能下降、精神症状和癫痫等边缘叶脑炎(limbic encephalitis,LE)的典型临床表现外,还可有上位脑干和间脑功能障碍的症状,而且多与肿瘤发生密切相关~([1])。血清和(或)脑脊液Ma2-Ab阳性患者常并发肿瘤,最常见于睾丸肿瘤~([2])及
[Abstract]:Antibody-associated encephalitis (Ma2) is an autoimmune encephalitis associated with anti-cellular antigens and antibodies, except for (limbic encephalitis, with reduced cognitive function, mental symptoms and epilepsy. In addition to the typical clinical manifestations of LE, there may also be symptoms of epistatic brainstem and diencephalon dysfunction, and most of them are closely related to tumorigenesis. Patients with Ma2-Ab positive in serum and / or cerebrospinal fluid (CSF) are often complicated with tumors, most commonly in testicular tumors ~ ([2]) and / or cerebrospinal fluid (CSF).
【作者单位】: 吉林大学白求恩第一医院神经内科和神经科学中心;
【分类号】:R742.9
本文编号:2391674
[Abstract]:Antibody-associated encephalitis (Ma2) is an autoimmune encephalitis associated with anti-cellular antigens and antibodies, except for (limbic encephalitis, with reduced cognitive function, mental symptoms and epilepsy. In addition to the typical clinical manifestations of LE, there may also be symptoms of epistatic brainstem and diencephalon dysfunction, and most of them are closely related to tumorigenesis. Patients with Ma2-Ab positive in serum and / or cerebrospinal fluid (CSF) are often complicated with tumors, most commonly in testicular tumors ~ ([2]) and / or cerebrospinal fluid (CSF).
【作者单位】: 吉林大学白求恩第一医院神经内科和神经科学中心;
【分类号】:R742.9
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1 Waragai M.;Chiba A.;Uchibori A.;刘凯;;表现为脑炎和进行性肌萎缩的抗Ma2相关副肿瘤性神经系统综合征[J];世界核心医学期刊文摘(神经病学分册);2006年04期
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