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脑出血、脑梗死急性发作期患者血压、血脂、凝血纤溶功能差异及意义

发布时间:2018-12-26 10:53
【摘要】:目的探讨脑出血、脑梗死急性发作期患者血压、血脂、凝血纤溶功能差异及其临床意义。方法选取脑出血急性发作期患者52例(脑出血组)、脑梗死急性发作期患者48例(脑梗死组),另选体检健康者40例(对照组),均测量SBP、DBP,检测血浆TC、TG、LDL-C、HDL-C、脂蛋白a[Lp(a)]及抗凝血酶Ⅲ(AT-Ⅲ)、纤维蛋白原(FIB)、蛋白C(PC)、D-二聚体(D-D)。结果脑出血组、脑梗死组SBP和DBP均高于对照组(P均0.05)。脑出血组血浆TG、LDL-C及Lp(a)水平均高于对照组,血浆TC、HDL-C水平均低于对照组;脑梗死组血浆TC、TG、LDLC及Lp(a)水平均高于对照组,血浆HDL-C水平低于对照组;脑出血组血浆TC、TG、LDL-C水平均低于脑梗死组;组间比较P均0.05。脑出血组、脑梗死组血浆FIB和D-D水平均高于对照组,血浆AT-Ⅲ水平均低于对照组;脑出血组PC活性高于脑梗死组及对照组;组间比较P均0.05。结论脑出血及脑梗死急性发作期患者均存在血压、血脂、凝血纤溶功能异常;脑梗死患者TC、TG、LDL-C水平及凝血纤溶亢进程度更高。
[Abstract]:Objective to investigate the difference of blood pressure, blood lipid, coagulation and fibrinolysis function in patients with cerebral hemorrhage and acute attack of cerebral infarction and its clinical significance. Methods 52 patients with acute attack of intracerebral hemorrhage (ICH group), 48 patients with acute cerebral infarction (CI group) and 40 healthy subjects (control group) were selected. Plasma TC,TG,LDL-C, was measured by SBP,DBP,. HDL-C, lipoprotein a [Lp (a)] and antithrombin 鈪,

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