丁苯酞注射液联合依达拉奉治疗急性脑梗死的疗效观察

发布时间：2019-01-03 11:32

【摘要】：目的观察丁苯酞注射液联合依达拉奉治疗急性脑梗死的临床效果。方法 90例急性脑梗死患者,按照随机数字表法分为联合组、丁苯酞组、依达拉奉组,各30例。联合组给予丁苯酞联合依达拉奉治疗、丁苯酞组采用单纯丁苯酞治疗、依达拉奉组采用单纯依达拉奉治疗。观察三组患者临床疗效。结果停药2周后,三组患者美国国立卫生卒中量表(NIHSS)评分较治疗前均降低,差异有统计学意义(P0.05);且联合组NIHSS评分为(5.1±2.6)分,低于丁苯酞组的(8.7±3.3)分和依达拉奉组的(9.1±3.5)分,差异有统计学意义(P0.05)。治疗后联合组颅脑CT改善优于丁苯酞组和依达拉奉组,差异有统计学意义(P0.05)。结论丁苯酞注射液联合依达拉奉可显著改善急性脑梗死患者的神经功能,降低脑组织缺血缺氧损伤。
[Abstract]:Objective to observe the clinical effect of butyphthalide injection combined with Edaravone in the treatment of acute cerebral infarction. Methods 90 patients with acute cerebral infarction were randomly divided into three groups: butyphthalide group and Edaravone group. The combined group was treated with butyphthalide combined with Edaravone, the butyphthalide group was treated with butyphthalide alone, and the Edaravone group was treated with Edaravone alone. To observe the clinical effect of three groups of patients. Results after two weeks of withdrawal, the (NIHSS) scores of the National Health Stroke scale in the three groups were significantly lower than those before treatment (P0.05). The NIHSS score of the combined group was (5.1 卤2.6), lower than that of the butyphthalide group (8.7 卤3.3) and the Edaravone group (9.1 卤3.5), the difference was statistically significant (P0.05). After treatment, the improvement of CT in combined group was better than that in butyphthalide group and Edaravone group, the difference was statistically significant (P0.05). Conclusion butyphthalide injection combined with Edaravone can significantly improve the neurological function of patients with acute cerebral infarction and reduce cerebral ischemia and hypoxia injury.
【作者单位】：大庆市人民医院神经内科;
【分类号】：R743.3

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