急性脑梗死患者应用依达拉奉与单唾液酸四己糖神经节苷脂钠治疗的效果分析

发布时间：2019-03-12 11:59

【摘要】：目的分析急性脑梗死患者应用依达拉奉与单唾液酸四己糖神经节苷脂钠治疗的效果。方法随机选择于2016年02月至2016年06月间我院收治的急性脑梗死患者96例,作为本次研究对象,采用电脑随机分组方式,将此次收治于我院的患者随机分为研究组与常规组,各组48例。其中常规组患者应用依达拉奉进行治疗;研究组患者应用依达拉奉与单唾液酸四己糖神经节苷脂钠治疗,对比两组患者临床治疗效果。结果研究组临床治疗总有效率显著高于常规组(91.67%VS 72.91%),数据对比具有统计学意义(P0.05),治疗前,两组日常生活活动能力量表BI评分、神经功能缺损量表NIHSS评分对比无差异意义(P0.05),治疗后,两组NIHSS、BI评分均得到显著改善,但研究组改善幅度显著优于常规组,组间数据对比差异显著(P0.05),不良反应方面,两组数据对比无差异意义(P0.05)。结论急性脑梗死患者应用依达拉奉与单唾液酸四己糖神经节苷脂钠治疗,疗效确切、突出,能有效恢复患者神经功能,改善患者日常生活能力,无严重不良反应,值得临床进一步推广应用。
[Abstract]:Objective to analyze the therapeutic effects of Edaravone and sodium monosialohexose ganglioside in patients with acute cerebral infarction. Methods 96 patients with acute cerebral infarction admitted to our hospital from February 2016 to June 2016 were randomly divided into study group and routine group. There were 48 cases in each group. The patients in the routine group were treated with Edaravone, and the patients in the study group were treated with Edaravone and sodium monosialohexosylganglioside, and the clinical effects were compared between the two groups. Results the total effective rate of clinical treatment in the study group was significantly higher than that in the routine group (91.67%VS 72.91%), and the data comparison was statistically significant (P0.05). Before treatment, the BI score of the activity of daily living scale in the two groups was significantly higher than that in the control group. There was no significant difference in NIHSS scores between the two groups (P0.05). After treatment, the NIHSS,BI scores in the two groups were significantly improved, but the improvement in the study group was significantly better than that in the routine group, and there was significant difference in the data comparison between the two groups (P0.05). There was no significant difference in adverse reactions between the two groups (P0.05). Conclusion Edaravone and sodium monosialohexose ganglioside are effective and prominent in the treatment of patients with acute cerebral infarction, which can effectively restore the neurological function and improve the ability of daily living of the patients without serious adverse reactions. It is worthy of further popularization and application in clinical practice.
【作者单位】：湖北省襄阳市谷城县中医医院内5科;
【分类号】：R743.33

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