血塞通注射液联合丁苯酞对急性脑梗死疗效及对患者神经功能的影响

发布时间：2019-05-03 19:57

【摘要】：目的探讨血塞通注射液联合丁苯酞对急性脑梗死(ACI)疗效及对患者神经功能的影响。方法选取2014年4月至2015年4月我院收治的120例ACI患者作为本次研究对象。按照随机数表法分为观察组和对照组两组,各60例,给予对照组口服丁苯酞治疗,每天3次,每次0.2 g;观察组在对照组的治疗上,进行血塞通注射液治疗(血塞通0.4 g,氯化钠注射液250 ml),静脉滴注,每天1次;观察两组患者的超氧化物歧化酶(SOD)、丙二醛(MDA)水平、神经功能缺损的改善情况、临床疗效。结果治疗后,观察组SOD(40.12±8.06 MU/L)优于对照组(35.21±7.16 MU/L),MDA(1.03±0.25 nmol/L)小于对照组(2.60±0.39 nmol/L)差异具有统计学意义(P0.05);观察组神经功能缺损的改善情况(5.02±4.30)%小于对照组(13.55±5.70)%差异具有统计学意义(P0.05);观察组疗效88.33%(53/60)优于对照组66.66%(40/60)差异具有统计学意义(P0.05);结论血塞通注射液联合丁苯酞对急性脑梗死疗效显著,有利于预后患者神经功能恢复。
[Abstract]:Objective to investigate the effect of Xuesaitong injection combined with buphthalide on (ACI) and neurological function of patients with acute cerebral infarction. Methods from April 2014 to April 2015, 120 patients with ACI were selected. They were divided into observation group (n = 60) and control group (n = 60) according to the method of random number table. The patients in control group were treated with buphthalide orally three times a day (0.2 g each time). In the control group, Xuesaitong injection (Xuesaitong 0.4 g, sodium chloride injection 250 ml), intravenous drip, once a day) was given to the control group. The level of superoxide dismutase (SOD), malondialdehyde (MDA) (MDA), the improvement of nerve function defect and the clinical effect were observed in the two groups. Results after treatment, the SOD in the observation group (40.12 卤8.06 MU/L) was better than that in the control group (35.21 卤7.16 MU/L), MDA (1.03 卤0.25 nmol/L), which was significantly lower than that in the control group (2.60 卤0.39 nmol/L) (P0.05). The improvement of nerve function defect in the observation group (5.02 卤4.30)% was significantly lower than that in the control group (13.55 卤5.70%) (P0.05). The curative effect of the observation group was 88.33% (53 / 60), which was better than that of the control group (66.66%) (P0.05). Conclusion Xuesaitong injection combined with buphthalide is effective in the treatment of acute cerebral infarction, which is beneficial to the recovery of neurological function in patients with prognosis.
【作者单位】：海南省保亭黎族苗族自治县人民医院内一科;海南省农垦总医院神经内科;
【分类号】：R743.33

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