脑苷肌肽与神经节苷脂钠治疗中枢性协调障碍的临床疗效对比

发布时间：2019-05-07 00:33

【摘要】：目的:比较脑苷肌肽与神经节苷脂钠治疗中枢性协调障碍(ZKS)患儿的疗效。方法:选取2013年10月至2015年8月广西梧州市妇幼保健院儿科收治的ZKS患儿90例,随机分为研究组和对照组,每组45例。在视听觉、触觉、运动、认知等综合训练的基础上,对照组采用神经节苷脂钠治疗,研究组采用脑苷肌肽治疗,两组均治疗3个疗程。比较两组患儿的临床疗效及发育商(DQ)。结果:研究组治疗总有效率为86.67%,与对照组(88.89%)比较,差异无统计学意义(P0.05);治疗后,对照组DQ评分为(97.88±12.53)分,研究组为(98.38±12.06)分,与治疗前比较均有明显提高(均P0.05),但治疗后两组间DQ评分比较,差异无统计学意义(P0.05)。结论:脑苷肌肽与神经节苷脂钠治疗ZKS患儿的疗效相当,在临床上均可酌情使用。
[Abstract]:Objective: to compare the efficacy of brain glycoside carnosine and ganglioside sodium in the treatment of central coordination disorder (ZKS). Methods: from October 2013 to August 2015, 90 children with ZKS were randomly divided into study group (n = 45) and control group (n = 45). On the basis of visual, auditory, tactile, motor and cognitive training, the control group was treated with ganglioside sodium, and the study group was treated with brain glycoside carnosine. Both groups were treated for 3 courses. Comparison of clinical efficacy and developmental quotient (DQ). Between the two groups Results: the total effective rate of the study group was 86.67%, compared with the control group (88.89%), there was no significant difference (P0.05). After treatment, the DQ score of the control group was (97.88 卤12.53), and that of the study group was (98.38 卤12.06), which was significantly higher than that of the pre-treatment group (all P0.05), but the DQ score of the two groups was compared after the treatment. There was no significant difference (P0.05). Conclusion: brain glycoside carnosine is similar to ganglioside sodium in the treatment of ZKS, and it can be used in clinic.
【作者单位】：广西梧州市妇幼保健院儿科;
【基金】：广西梧州市科学研究与技术开发计划资助项目(No.201101073)
【分类号】：R741

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