中青年缺血性脑卒中CISS分型的临床特点及预后

发布时间：2019-05-08 16:57

【摘要】：目的:比较不同中青年缺血性脑卒中患者的CISS分型发病的临床特点及预后的分析。方法:收集从2011年1月-2015年11月共96例入住广西壮族自治区人民医院神经内科的18岁-59岁的缺血性脑卒中患者的人口学情况、发病后第一次入院的检查及检验数据,在2016年12月进行电话随访,分别记录患者是否坚持脑卒中二级预防,是否留下后遗症及mRS,是否复发或死亡;将患者进行CISS分型,分析CISS各亚型的缺血性脑卒中临床特点,为缺血性脑卒中的预防提供帮助。结果:本次研究的结果如下:CISS分型:大动脉硬化型(large artery atherosclerosis type LAA 39例40.6%),心源性(cardiogenic stroke CS 9例9.4%),穿支动脉型(perforator artery type PAD 42例43.7%),其它病因(other etiology 4例OE4.2%)、病因不明(undetermined etiology UE 2例2.1%),CISS分型中胆红素、房颤、年龄在组间比较有统计学差异(P0.05),各亚型缺血性脑卒中病死率及复发率差异无统计学意义(P0.05)。结论:中青年缺血性脑卒中CISS分型各亚型与高血压、糖尿病、吸烟等及C反应蛋白、尿酸无统计学相关,胆红素、房颤、年龄有统计学相关性,不同CISS分型的临床特点及预后无统计学相关性,但其中穿支动脉病变复发率和死亡率相对较高。
[Abstract]:Objective: to compare the clinical features and prognosis of CISS typing in different middle-aged and young patients with ischemic stroke. Methods: from January 2011 to November 2015, 96 patients aged 18-59 years old with ischemic stroke who were admitted to the Department of Neurology of Guangxi Zhuang Autonomous region people's Hospital were collected. A telephone follow-up was conducted in December 2016 to record whether the patients insisted on secondary prevention of stroke, whether the sequelae were left behind, and whether mRS, recurred or died. The patients were classified by CISS, and the clinical characteristics of ischemic stroke of CISS subtypes were analyzed in order to provide help for the prevention of ischemic stroke. Results: the results of this study were as follows: CISS classification: 39 cases of atherosclerotic (large artery atherosclerosis type LAA (40.6%), 9 cases of cardiogenic (cardiogenic stroke CS (9.4%), 42 cases of perforating artery type (perforator artery type PAD (43.7%). Other etiology of (other etiology 4 cases of OE4.2%, 2 cases of unknown etiology of (undetermined etiology UE 2.1%), CISS classification of bilirubin, atrial fibrillation, age was statistically different between groups (P0.05). There was no significant difference in mortality and recurrence rate of ischemic stroke among subtypes (P0.05). Conclusion: there is no significant correlation between CISS subtypes and hypertension, diabetes mellitus, smoking, C-reactive protein, uric acid, bilirubin, atrial fibrillation and age in middle-aged and young patients with ischemic stroke. There was no statistical correlation between the clinical features and prognosis of different CISS classification, but the recurrence rate and mortality rate of perforating artery disease were relatively high.
【学位授予单位】：广西中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R743.3

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