P62蛋白的研究
发布时间：2019-06-06 05:43
【摘要】：正P62蛋白(sequestosome 1)是自噬选择性底物,在形成细胞质蛋白包涵体的过程中起到关键的作用,是阿尔茨海默病(Alzheimer's disease,AD)、帕金森病(Parkinson's disease,PD)和许多慢性退行性疾病的标志物[1]。本综述讨论p62蛋白的生理作用及其分子机制。一、p62蛋白人类的p62蛋白基因位于5号染色体,p62蛋白含有440
[Abstract]:Positive p62 protein (sequestosome 1) is an autophagy selective substrate, which plays a key role in the formation of cytoplasmic protein inclusion bodies. It is Alzheimer's disease (Alzheimer's disease,AD) and Parkinson's disease (Parkinson's disease,). PD) and many markers of chronic degenerative diseases [1]. In this review, the physiological function and molecular mechanism of p62 protein were discussed. One, p62 protein human p62 protein gene is located on chromosome 5, p62 protein contains 440
【作者单位】： 邢台市第三医院神经内科;邢台市第三医院体检中心;河北医科大学第二医院神经病学重点实验室;
【分类号】：R741
，
本文编号：2494111
[Abstract]:Positive p62 protein (sequestosome 1) is an autophagy selective substrate, which plays a key role in the formation of cytoplasmic protein inclusion bodies. It is Alzheimer's disease (Alzheimer's disease,AD) and Parkinson's disease (Parkinson's disease,). PD) and many markers of chronic degenerative diseases [1]. In this review, the physiological function and molecular mechanism of p62 protein were discussed. One, p62 protein human p62 protein gene is located on chromosome 5, p62 protein contains 440
【作者单位】： 邢台市第三医院神经内科;邢台市第三医院体检中心;河北医科大学第二医院神经病学重点实验室;
【分类号】：R741
，
本文编号：2494111
本文链接：https://www.wllwen.com/yixuelunwen/shenjingyixue/2494111.html
最近更新
教材专著
