临床治疗三叉神经痛的阿霉素最佳浓度探究

发布时间：2019-06-19 00:09

【摘要】：目的探讨临床治疗三叉神经痛的阿霉素最佳浓度。方法入组对象为2014年5月至2017年5月入住本院的90例PTN患者,均符合2004年国际头痛学分会分类委员会制定的《头痛的国际分类》中关于PTN的临床诊断标准。将其按照治疗方法分为Ⅰ、Ⅱ、Ⅲ组,各为30例。分别采用0.33%及0.50%及1.0%浓度的阿霉素进行治疗,比较三组临床疗效。结果 (1)3组组治疗后VAS疼痛评分均显著小于治疗前(P0.05),且Ⅱ、Ⅲ组患者治疗后VAS评分显著小于Ⅰ组治疗后(P0.05);(2)经治疗后,Ⅰ组临床总有效率为73.33%(22/30),Ⅱ组为96.67%(29/30),Ⅲ组为96.67%(29/30),Ⅱ、Ⅲ组患者治疗疗效显著优于Ⅰ组(P0.05)。结论 0.5%及1.0%浓度的阿霉素治疗PTN的疗效及安全性均较高,应在临床中进行推广。
[Abstract]:Objective to investigate the optimal concentration of doxorubicin in clinical treatment of trigeminal neuralgia. Methods 90 PTN patients admitted to our hospital from May 2014 to May 2017 were enrolled in the study. All of them met the clinical diagnostic criteria of PTN in the International Classification of headache established by the International Classification of headache in 2004. According to the treatment method, they were divided into three groups, 30 cases in each group. The clinical effects of 0.33% and 0.50% and 1.0% doxorubicin were compared among the three groups. Results (1) the VAS pain score of the three groups after treatment was significantly lower than that before treatment (P 0.05), and the VAS score of the patients in group II and III after treatment was significantly lower than that after treatment in group 鈪，

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