中国人群脑卒中发病影响因素Meta分析

发布时间：2019-08-07 12:55

【摘要】：目的综合分析中国人群脑卒中发病的影响因素。方法对2005年1月-2014年7月国内外公开发表的关于中国人群脑卒中发病影响因素的文献进行Meta分析。结果共纳入69篇文献,累计病例组患者24 775例,对照组人群31 197人;定性因素中,高血压、糖尿病、高脂血症、心脏病、吸烟、饮酒、超重、高血压家族史的比值比(OR值)均1,体育锻炼的OR值1,差异有统计学意义(P0.05);定量因素中,体重指数(BMI)、收缩压(SBP)、舒张压(DBP)、空腹血糖(FBG)、糖化血红蛋白(Hb A1c)、尿酸(UA)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)的平均差(MDI)均1,高密度脂蛋白胆固醇(HDL-C)的MDI0,差异有统计学意义(P0.05)。敏感性分析:除体育锻炼和高血压家族史外,其他各因素的结果均稳定;Egger's检验:纳入的文献不存在发表偏倚。结论高血压、糖尿病、高脂血症、心脏病、吸烟、饮酒、超重、高血压家族史和体育锻炼是中国人群脑卒中发病影响因素。
[Abstract]:Objective to analyze the influencing factors of stroke in Chinese population. Methods the literatures published at home and abroad from January 2005 to July 2014 on the influencing factors of stroke in Chinese population were analyzed by Meta. Results A total of 69 articles were included, 24 775 patients in the case group and 31 197 in the control group, the ratio of hypertension, diabetes, hyperlipidemia, heart disease, smoking, drinking, overweight and hypertension family history (OR value) was 1, and the OR value of physical exercise was 1, the difference was statistically significant (P 0.05). Among the quantitative factors, body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting blood glucose (FBG), glycosylated hemoglobin (Hb A1c), uric acid (UA), glycerol (TG), low density lipoprotein cholesterol (LDL-C) average difference (MDI) 1, high density lipoprotein cholesterol (HDL-C) MDI0, difference was statistically significant (P 0.05). Sensitivity analysis: except for the family history of physical exercise and hypertension, the results of other factors were stable. Egger's test: there was no publication bias in the included literature. Conclusion Hypertension, diabetes mellitus, hyperlipidemia, heart disease, smoking, drinking, overweight, family history of hypertension and physical exercise are the influencing factors of stroke in Chinese population.
【作者单位】：厦门大学公共卫生学院;卫生技术评估福建省高校重点实验室;
【基金】：厦门市科技计划项目(3502Z20143006) 大学生创新项目(2015Y0937)
【分类号】：R743.3

【相似文献】