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面神经F波用于评估中国听神经瘤患者术前术中术后面神经功能的研究

发布时间:2021-05-27 10:17
  目的:本对119例经显微手术治疗的听神经瘤(VS)患者进行回顾性分析及术后随访,评估面神经F波各项电生理参数与面神经功能障碍的关系,同时一并分析面神经功能与肿瘤大小,内听道直径(IAM),术后局部出血以及术前、术中、术后面神经F波参数的关系。方法资料:对中南大学湘雅医院颅底外科中心自2011年7月至2012年10月间由袁贤瑞教授主刀的119例听神经瘤病例进行回顾分析,所有病例均经枕下乙状窦后内听道入路切除肿瘤。所有患者术前均完善颅底HRCT及颅脑平扫增强MRI检查,并在术前,术中及术后进行面神经F波电生理评测。术中详细记录了听神经瘤的大小和类型以及肿瘤与面神经的关系。多数患者接受手术治疗后存在面神经功能障碍。以House-Brackmann (HB)面神经功能分级作为面神经功能评价指标。对所有病例术后过15天,3个月,6个月,9个月和1年的时段定期进行随访,观察肿瘤是否复发,术后面神经瘫痪程度及面部F波的评估。结果119例患者中,1例属于复发再次手术病例,术前HB分级为Ⅳ级。而且该患者术前、术中F波检测没有波形,因此排除,118例纳入统计分析。在这118例患者中,2(1.69%)例属于... 

【文章来源】:中南大学湖南省 211工程院校 985工程院校 教育部直属院校

【文章页数】:88 页

【学位级别】:硕士

【文章目录】:
摘要
ABSTRACT
Table of Abbreviations
Preface
    Overview
    Operative technique
    Significance of research
    Facial F-wave Monitoring
Ⅰ.Clinical Materials and Methods.第一章 资料与方法
    1.1. Overview
    1.2. Clinical Manifestation of VS
    1.3. Pre-operative Investigations
    1.4. Facial F-wave recording
    1.5. Facial F-waves parameters
    1.6. Surgical technique
    1.7. Patients grouping and post-operative outcomes
    1.8. Statistical analysis
Ⅱ Results
    2.1. Patients' data
    2.2. Size of VS& IAM
    2.3. Preoperative HB Score and Facial F-wave parameters
    2.4. Postoperative HB Score and Facial F-wave parameters
    2.5. Intraoperative Facial F-wave parameters
    2.6. Follow-up HB Scores & VS recurrence
    2.7. Correlation between parameters of Facial F-wave and dimension of VS,IAM & postoperative hemorrhage
    2.8. Correlation regarding Pre-operative HB score
    2.9. Correlation regarding Post-operative HB score
    2.10. Correlation rega rding follow-up HB scores
Ⅲ.Discussion
    3.1. Overview
    3.2. Sensitivity of different F-wave parameters
    3.3. Pre-operative HB score and its correlation with IAM & size ofVS
    3.4. Pre-operative HB score and its correlation with F-waveparameters
    3.5. Post-operative HB score and its correlation with F-waveparameters
    3.6. Post-operative HB score and its correlation with post-operativehemorrhage
    3.7. Follow-up HB scores and its correlation with F-waveparameters
Ⅳ. Conclusion
Ⅴ. Prospective
Ⅵ. References
Review
    Overview
    Intra-operative Facial nerve monitoring
    EMG monitoring
    F wave monitoring
    Characteristics of CN Ⅶ Dysfunction in VS
    Sensitivity of F-wave parameters
    Conclusion
    References
Chinese summary 中文介绍
Acknowledgement
Personal Identity



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