带血管蒂髌腱移植物的力学性能

发布时间：2018-01-12 17:18

本文关键词：带血管蒂髌腱移植物的力学性能　出处：《中国组织工程研究》2015年47期 　论文类型：期刊论文

【摘要】：背景:临床上研究膝关节交叉韧带生物材料的力学性能具有重要意义,可为临床研制组织结构、生物力学及相容性好的材料提供理论依据。目的:分析带血管蒂髌腱移植物的力学性能。方法:切断42只新西兰大白兔左前腿前交叉韧带,随机分为2组,实验组植入自体带血管蒂髌腱移植物进行前交叉韧带修复,对照组植入自体不带血管蒂髌腱移植物进行前交叉韧带修复。移植后8,12,16周,检测两组移植标本的生物力学性能。结果与结论:两组不同时间点的断裂位置比较差异无显著性意义;实验组移植后12,16周的膝关节前后松弛度高于对照组(P0.05),两组移植后8周的膝关节前后松弛度比较差异无显著性意义;实验组移植后8,12,16周的最大载荷均高于对照组(P0.05),移植后8,12,16周的刚度均高于对照组(P0.05);两组移植后不同时间点的最大拉伸长度比较差异无显著性意义。表明带血管蒂髌腱移植物具有良好的力学性能。
[Abstract]:Background: it is of great significance to study the mechanical properties of knee cruciate ligament biomaterials in clinic and can be used to develop tissue structure for clinical application. Objective: to analyze the mechanical properties of patellar tendon grafts with vascular pedicle. Methods: 42 New Zealand white rabbits were randomly divided into 2 groups. The experimental group was implanted with autogenous patellar tendon graft with vascular pedicle for anterior cruciate ligament repair, while the control group was implanted with autogenous patellar tendon graft without vascular pedicle for anterior cruciate ligament repair. Results and conclusion: there was no significant difference in fracture location between the two groups at different time points. The relaxation degree of the knee joint in the experimental group was higher than that in the control group at 12 and 16 weeks after transplantation, but there was no significant difference between the two groups in the relaxation of the knee joint at the 8th week after transplantation. The maximum load of the experimental group at the 16th week after transplantation was higher than that of the control group (P 0.05), and the stiffness of the control group at the week 81216 was higher than that of the control group (P 0.05). There was no significant difference in the maximum stretch length between the two groups at different time points after transplantation, which indicated that the patellar tendon grafts with vascular pedicle had good mechanical properties.
【作者单位】：新疆医科大学第六附属医院;
【分类号】：R687;R318.08
【正文快照】： 0引言Introduction膝关节在人体直立、行走、跳跃中发挥了重要的作用,其结构对于身体稳定性和灵活性有着更好的要求。从人体膝关节解剖结构来看:保护机体膝关节稳定性的韧带关节囊网则属于内源性稳定装置,它主要由关节囊、关节各类韧带组成。而膝关节韧带属于韧带关节囊中比较

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