钛网内固定系统重建胸腰段肿瘤切除后脊柱:稳定性及生物相容性

发布时间：2018-01-14 22:20

本文关键词：钛网内固定系统重建胸腰段肿瘤切除后脊柱:稳定性及生物相容性　出处：《中国组织工程研究》2015年21期 　论文类型：期刊论文

【摘要】：背景:脊柱胸腰段肿瘤切除后会对脊柱的稳定性产生较大的影响,临床需要积极的进行内固定,以维持良好的脊柱稳定性。利用钛网植入联合内固定的方式,可以为肿瘤切除后提供坚强内固定。目的:观察钛网内固定系统重建脊柱胸腰段肿瘤切除后的脊柱稳定性及与宿主的生物相容性。方法:从遂宁市中心医院2012年9月至2014年9月收治的脊柱胸腰段肿瘤患者中随机选择24例进行研究,均实施肿瘤切除治疗,并联合予以钛网植骨植入缺损区+前路内固定。治疗后随访1-12个月,观察患者的神经功能恢复情况及脊柱稳定性,并进行分析。结果与结论:入组的24例脊柱胸腰段肿瘤患者均顺利完成治疗,至随访结束未出现死亡病例。患者的临床症状和神经功能均得到显著缓解,治疗前后Frankel分级情况得到显著改善。且经定期X射线片检查,24例患者的钛网及前路内固定系统位置均未出现改变,且未出现钛网塌陷、内固定断裂松动等情况,脊柱稳定性良好。表明脊柱胸腰段肿瘤切除联合钛网植入+前路内固定可以重建脊柱稳定性,获得良好的临床效果,且生物相容性好。
[Abstract]:Background: thoracolumbar spine tumor resection will have a greater impact on the stability of the spine, clinical needs to actively carry out internal fixation to maintain good spinal stability. Titanium mesh implantation combined with internal fixation. Objective: to observe the stability of spine and its biocompatibility with host after thoracolumbar tumor resection with titanium mesh internal fixation system. From September 2012 to September 2014, 24 patients with thoracolumbar spinal tumors were randomly selected from Suining Central Hospital. All patients were treated with tumor resection and combined with titanium mesh bone graft and anterior internal fixation in defect area. The patients were followed up for 1-12 months to observe the recovery of nerve function and spinal stability. Results and conclusion: 24 patients with thoracolumbar spinal tumors were successfully treated, and no death cases were found at the end of follow-up. The clinical symptoms and neurological function of the patients were significantly alleviated. The Frankel grading was significantly improved before and after treatment, and the location of titanium mesh and anterior internal fixation system did not change in 24 patients after regular X-ray examination, and no titanium mesh collapse was found. The stability of spinal column was good in the case of fracture and loosening of internal fixation, which indicated that thoracolumbar tumor resection combined with anterior fixation with titanium mesh could reconstruct spinal stability, obtain good clinical effect, and have good biocompatibility.
【作者单位】：遂宁市中心医院骨科中心骨二病区;
【基金】：四川省遂宁市中心医院骨科中心
【分类号】：R318.08;R738.1
【正文快照】： 文章亮点:1肿瘤椎体切除后,由于前、中、后柱的支撑、承载及缓冲功能的连续性均遭到中断,因而椎节的高度及椎管容积明显减少,脊柱部分或全部失稳,需要重建脊柱的结构及生物力学稳定性。2试验创新性地采用钛网支撑植骨联合内固定重建肿瘤切除后的脊柱稳定,发现这种方法具有良好

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