多参数可调经颅微电流刺激仪的研制和基于脑电的效果评测

发布时间：2018-02-14 08:17

本文关键词： 经颅微电流刺激脑电 α波恒流模块　出处：《中国生物医学工程学报》2015年06期 　论文类型：期刊论文

【摘要】：经颅微电流刺激已被广泛用于改善和治疗焦虑、抑郁和失眠等不适应症。研制一种波形、脉宽、重复频率和强度等多参数可调的经颅微电流刺激仪。在设备开发中,为避免个体头部阻抗差异导致的刺激电流强度变化,利用恒流模块实现相同强度的脑部刺激电流。为评估刺激效果,招募20个志愿者进行实际测试。通过脑电频谱分析和双因素重复方差分析方法,对不同刺激波形在刺激前后的脑电α频段频谱含量进行评估。评估结果表明,α频段频谱含量在刺激参数和刺激前后两个因素的交互作用显著(P0.01),4种波形(方波、三角波、锯齿波、正弦波)均能在不同程度上有效提升α频段频谱含量,且正弦波刺激能显著提高EEGα频段的频谱含量(功率谱占比提高20%以上),由此证明设备的有效性。
[Abstract]:Transcranial microcurrent stimulation has been widely used to improve and treat unsuitable conditions such as anxiety, depression and insomnia. A transcranial microcurrent stimulator with multiple parameters, such as waveform, pulse width, repetition rate and intensity, has been developed. In order to avoid the change of stimulation current intensity caused by the difference of head impedance, the constant current module was used to realize the same intensity of brain stimulation current. Twenty volunteers were recruited for the actual test. EEG spectrum analysis and double factor repeated variance analysis were used. The spectrum content of 伪 -band of EEG before and after stimulation was evaluated. The results showed that the interaction of the two factors before and after stimulation was significant (square wave, triangle wave, sawtooth wave, square wave, triangle wave, sawtooth wave). Sinusoidal wave can effectively increase the frequency spectrum content of 伪 band in varying degrees, and sine wave stimulation can significantly increase the frequency spectrum content of EEG 伪 band (the power spectrum ratio is increased by more than 20%), which proves the validity of the equipment.
【作者单位】：北京信息科技大学信息与通信工程学院;浙江大学第一附属医院肝胆胰外科;工业和信息化部电信研究院泰尔终端实验室;
【基金】：北京信息科技大学人才培养项目
【分类号】：R741.044

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