粉针剂间歇计量与连续充填装置的协同设计

发布时间：2018-02-23 12:25

本文关键词： 粉针剂螺杆计量连续充填压电振动协同设计仿真分析　出处：《哈尔滨商业大学》2012年硕士论文　论文类型：学位论文

【摘要】：粉针剂分装机是制药行业的重要设备。由于分装速度、精度与剂量变化适应性等技术指标均达不到国际领先水平,而且新产品开发周期长、设计手段落后,使得国产分装机缺乏市场竞争力。因此,利用现代设计方法,对粉针剂分装机的关键部件—计量与充填装置进行结构与工作参数的协同设计,显得尤为关键,具有非常现实的意义。论文分析了粉针剂的物性,深入研究了粉针剂的流动性、松装密度等特性与分装速度、分装精度的关系,分析了粉状物料的计量与充填方式,确定了基于间歇式螺杆计量、连续式压电振动充填的粉针剂计量充填研究方案,以克服粉针剂物性对分装速度和精度的影响。建立精密计量螺杆的数学模型,结合SolidWorks二次开发模块和VB,建立了计量螺杆的参数化快速设计功能模块。详细设计计量螺杆、搅拌叶片与粉杯的结构参数,以改善传统容积计量调节困难的缺陷。采用伺服电机直连计量螺杆的方式,精确控制螺杆的转动,保证计量精度。选用压电双晶片作为振动驱动源,合理设计了溜槽与板弹簧的结构参数,提出了此种振型固有频率的计算方法,并拟定了粉针剂在输送料盘上的理想运动过程,确定跳跃边界条件。采用压电双晶片驱动的方式,设计了新型的粉料压电振动充填装置；分析了粉针剂的振动输送与充填的机理,确定粉针剂振动输送边界条件。提出机构固有频率的计算方法,优化设计了溜槽与板弹簧的结构参数,以提高压电振动充填装置性能。深入分析了装置计量与充填协同工作的工作原理,确定两装置在容积量与时间两个方面的协同工作参数,并以工作循环图的方式表示整个计量充填周期的工作过程。利用SolidWorks软件构造计量与充填装置的三维模型,结合COSMOS Motion模块进行运动学仿真,确定了装置的最佳工作参数,并输出相应的曲线,得出了系统达到最大充填速度的振动频率为10Hz,振动送料器的最大旋转速度为7.95rad/s。此外,还对板弹簧做了力学分析,验证模型的合理性和可行性。
[Abstract]:Powder dispensing machine is an important equipment in the pharmaceutical industry. Due to the technical indexes such as speed, accuracy and adaptability of dosage change, it can not reach the international leading level, and the new product development cycle is long, and the design means lag behind. Therefore, it is very important to use modern design method to design the structure and working parameters of the key parts of powder dispenser, metering and filling device. Has very realistic significance. In this paper, the physical properties of the powder injection are analyzed, and the relationship between the fluidity and the loose density of the powder injection and the speed and precision of the powder injection is studied. The metering and filling method of the powder material is analyzed, and the metering method based on the intermittent screw is determined. In order to overcome the influence of the physical properties of powder injection on the speed and accuracy of split filling, the research scheme of continuous piezoelectric vibration filling is presented in this paper. The mathematical model of precision measuring screw was established. The parameterized and rapid design function module of metering screw was established with the combination of SolidWorks secondary development module and VB. The structural parameters of metering screw, agitating blade and powder cup were designed in detail. In order to improve the defects of the traditional volume measurement adjustment, the servo motor is directly connected with the measuring screw to accurately control the screw rotation and ensure the measurement accuracy. The piezoelectric bimorph is chosen as the vibration driving source, the structural parameters of the chute and plate spring are reasonably designed, the calculation method of the natural frequency of the vibration mode is put forward, and the ideal movement process of the powder injection on the conveying plate is worked out. Determine the jump boundary conditions. A new type of piezoelectric vibration filling device is designed by using piezoelectric bimorph drive, the mechanism of vibrating conveying and filling of powder injection is analyzed, the boundary condition of vibrating conveying of powder injection is determined, and the method of calculating the natural frequency of mechanism is put forward. The structural parameters of chute and plate spring are optimized to improve the performance of piezoelectric vibration filling device. The working principle of cooperative work between metering and filling is deeply analyzed, and the cooperative working parameters of the two devices in volume and time are determined. The working process of the whole metering and filling cycle is represented by the working cycle diagram. The 3D model of the metering and filling device is constructed by using SolidWorks software, and the kinematics simulation is carried out with the COSMOS Motion module, and the optimum working parameters of the device are determined. The corresponding curves are outputted, the vibration frequency of the system reaching the maximum filling speed is 10 Hz and the maximum rotating velocity of the vibrating feeder is 7.95 radr / s. In addition, the mechanical analysis of the plate spring is done to verify the rationality and feasibility of the model.
【学位授予单位】：哈尔滨商业大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：TH788;TP391.72

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