细胞片层技术在口腔组织工程中的研究进展

发布时间：2018-03-08 21:33

本文选题：细胞片层技术　切入点：口腔组织工程　出处：《中国修复重建外科杂志》2014年09期 　论文类型：期刊论文

【摘要】：目的细胞片层技术(cell sheet technology,CST)克服了传统组织工程中的缺点,展示了在组织工程中的革新和优势。现就CST及其在口腔组织工程领域的研究进展进行综述。方法查阅近年来国内外关于CST以及在口腔组织工程中研究及应用的相关文献,进行分析、整理和总结。结果与传统组织工程技术相比,CST细胞接种率高、基质丰富、具有良好的生物相容性和理想操作性,有利于细胞移植成活和组织功能重建。CST在口腔牙周组织修复重建、口腔黏膜软组织缺损修复以及颌面部骨缺损修复中均有成功研究报道。结论 CST不断改进,并与传统组织工程技术相结合将会促进口腔组织工程学进一步发展。
[Abstract]:Objective to overcome the shortcomings of traditional tissue engineering by cell lamellar technique (CSTs). The innovation and advantages in tissue engineering were demonstrated. The research progress of CST and its application in oral tissue engineering was reviewed. Methods the literatures on CST and its application in oral tissue engineering were reviewed in recent years. The results showed that compared with the traditional tissue engineering technology, the cell contact rate of CST was higher, the matrix was abundant, and had good biocompatibility and ideal maneuverability. It is beneficial to the survival of cell transplantation and the reconstruction of tissue function. CST has been reported successfully in oral periodontal tissue repair, oral mucosal soft tissue defect repair and maxillofacial bone defect repair. Conclusion CST is continuously improved. Combining with traditional tissue engineering technology will promote the further development of oral tissue engineering.
【作者单位】：川北医学院附属医院口腔科;
【基金】：国家自然科学基金资助项目(81102063)~~
【分类号】：R318.0

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