可控分子组装的自驱动胶体马达及其生物医学应用

发布时间：2018-03-23 10:58

本文选题：胶体马达　切入点：可控分子组装　出处：《中国科学:化学》2017年01期

【摘要】：人造胶体马达是能够将不同形式的能量转化为流体中机械运动的微纳米机器.自2 0 1 2年以来,将自下而上的可控分子组装与自上而下的方法有效结合已成为可控构筑胶体马达的重要策略之一.基于可控分子组装(如层层组装)的胶体马达具有易于实现规模化制备、能够对外界刺激作出响应、便于实现多功能化等优点.本文综述了通过将各种功能性构筑基元集成到组装结构中进而实现胶体马达的可控构筑、运动控制以及生物医学应用等方面的研究进展.主要介绍了基于不同层层组装结构的气泡驱动马达的可控构筑,基于聚电解质多层膜微胶囊及纳米管的近红外光驱动马达的构筑,生物界面化马达的制备,实现对胶体马达运动速度、方向及状态有效控制的主要方法,以及马达在药物靶向递送、光热治疗和生物毒素清除等生物医学领域中的应用.
[Abstract]:Artificial colloid motor is a micro and nano machine that can convert different forms of energy into mechanical motion in fluid. The effective combination of bottom-up controllable molecular assembly and top-down method has become one of the important strategies for the controllable construction of colloidal motors. The colloidal motors based on controllable molecular assembly (such as layer-by-layer assembly) are easy to be prepared on a large scale. This paper reviews the controllable construction of colloidal motor by integrating various functional building elements into the assembly structure. Research progress in motion control and biomedical applications. The controllable construction of bubble driven motors based on different layers of assembly structures is introduced. Based on the construction of polyelectrolyte multilayer film microcapsule and nanotube near-infrared light driving motor and the preparation of biological interfacial motor, the main methods to effectively control the speed, direction and state of the colloidal motor are realized. Motor applications in biomedical applications such as drug targeting delivery, photothermal therapy and biotoxin clearance.
【作者单位】：哈尔滨工业大学微系统与微结构制造教育部重点实验室微纳米技术研究中心;
【基金】：国家自然科学基金(编号:21573053,21674029,21603047)资助项目
【分类号】：O648.1;R318

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