数值模拟松质骨中流动电势分布

发布时间：2018-03-30 02:28

本文选题：松质骨　切入点：细观模型　出处：《医用生物力学》2015年02期

【摘要】：目的对压力驱动下一种松质骨细观模型产生的流动电势进行数值模拟分析,了解流动电势在松质骨中的分布特点。方法根据电场和流体的控制方程,利用有限单元法计算该松质骨模型在一定压力下产生的稳态流动电势。结果松质骨模型中靠近固体表面的流动电势较大,约为43.4μV;而远离固体表面的流动电势较小,约为19.7μV。压力和Zeta电势对模型的流动电势影响比较大,并且呈线性增长的关系。离子数浓度较低时,离子数浓度对流动电势的影响较大;当离子数浓度较高时,离子数浓度对流动电势的影响很小。结论研究结果为利用电流、电磁场刺激等方法防治和治疗临床骨折、老年性骨质疏松及其他骨科疾病提供相关的理论依据。
[Abstract]:Objective to study the distribution of fluid potential in cancellous bone by numerical simulation of the flow potential generated by a meso-model of cancellous bone driven by pressure. Methods according to the governing equations of electric field and fluid, the distribution of flow potential in cancellous bone was studied. The finite element method was used to calculate the steady flow potential of the cancellous bone model under a certain pressure. Results the flow potential near the solid surface in the cancellous bone model was larger, about 43.4 渭 V, but the flow potential far away from the solid surface was smaller. The effect of pressure and Zeta potential on the flow potential of the model is relatively large, and it is linearly increased. When the concentration of ion number is low, the influence of ion number concentration on the flow potential is greater, and when the ion number concentration is higher, the influence of ion number concentration on the flow potential is greater. Conclusion the results provide a theoretical basis for the prevention and treatment of clinical fractures, senile osteoporosis and other orthopaedic diseases by means of electric current and electromagnetic stimulation.
【作者单位】：暨南大学力学与土木工程系;
【基金】：国家自然科学基金重点项目(11032005)
【分类号】：O441;R318.01

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