医用二氧化碳吸收剂的制备工艺和产业化研究

发布时间：2018-03-31 02:24

  本文选题：二氧化碳吸收剂　切入点：强度　出处：《浙江大学》2012年硕士论文

【摘要】：在临床低流量封闭式麻醉系统中,需要有一种安全高效的二氧化碳吸收剂对病人呼吸产生的二氧化碳进行及时快速的吸收。这种医用二氧化碳吸收剂分为钠石灰(钠含量高于3wt%)和钙石灰(钠含量低于1wt%),前者会与麻醉系统中的麻醉剂发生毒性反应生成有毒物质CO和“化合物A”,但拥有很高的强度和吸收率。这里的强度是指产品放置一段时间后出现的粉尘的大小。后者与麻醉剂呈惰性,但是强度和吸收率略显不足。目前国产的二氧化碳吸收剂强度低,吸收率也较低。 本文的主要工作是在研究出钠石灰的配方和制备工艺后,并成功放大化实验室制备方法并实现了产业化生产,并使产品的性能与实验室制备的试样相比有了显著的提升。 实验结果表明：硅铝酸钠含量在4wt%左右时就能很好的起到增强剂的作用,继续提高含量,产品强度基本不变而吸收率显著下降。热处理温度增加,产品强度越好,热处理在100-120℃处理5-15min时便可获得理想的强度值。在产品中加入聚乙烯醇(2wt%)就能在基本不影响强度和吸收率的情况下有效防止产品出现粉化现象。 另外,本文还对钙石灰进行了初步的研究,实验结果显示再取代氢氧化钠的物质中,LiOH和三乙醇胺都基本能起到碱性剂的作用。 目前,钠石灰已经成功投入工业化生产,拥有了年产千吨级,经济效益达百万元级的钠石灰生产线。
[Abstract]:In clinical low flow closed anesthesia systems, A safe and efficient carbon dioxide absorbent is needed for the rapid and timely absorption of carbon dioxide produced by the patient's breathing. This medical carbon dioxide absorbent is divided into sodium lime (sodium content higher than 3 wtts) and calcium lime (sodium content). Less than 1 wt. the former produces toxic substances CO and "compound A" by toxic reactions with anesthetics in the anesthetic system, but it has a high strength and absorptivity. The strength here refers to the dust that occurs after the product has been placed for a period of time. Size. The latter is inert with the anesthetic, However, the intensity and absorptivity of carbon dioxide absorbents are low and the absorptivity is low. The main work of this paper is to study the formulation and preparation process of sodium lime, and to amplify the laboratory preparation method and realize the industrial production successfully, and make the performance of the product obviously improved compared with the sample prepared in the laboratory. The experimental results show that the content of sodium aluminate can play a good role as an enhancer when the content of sodium silicate is about 4 wt%. The strength of the product is basically unchanged and the absorptivity is significantly decreased when the content of sodium silicate continues to increase. The higher the heat treatment temperature is, the better the strength of the product is. The ideal strength value can be obtained when 5-15min is treated at 100-120 鈩，

本文编号：1688750