视网膜电图在早产儿视网膜病变激光术后视网膜功能评价中的应用

发布时间：2018-05-07 13:54

本文选题：早产儿视网膜病变 + 激光光凝　；参考：《眼科新进展》2014年06期

【摘要】：目的应用视网膜电图(electroretinogram,ERG)评价早产儿视网膜病变(retinopathy of premature,ROP)激光术后视网膜功能的变化。方法选取2011年1月至2012年12月在我院行激光光凝术的ROP患儿30例(60眼)为观察组,另选取同期视网膜发育正常的健康早产儿30例(60眼)为对照组,记录激光术后6个月的暗适应与明适应ERG,并对两组结果进行统计比较。结果观察组视杆反应b波振幅为(131.47±36.20)μV,对照组为(149.33±40.14)μV,差异有统计学意义(P0.05);观察组最大混合反应a波、b波振幅分别为(96.52±23.71)μV、(222.76±53.44)μV,对照组分别为(109.85±23.17)μV、(260.44±52.28)μV,差异均有统计学意义(均为P0.05);观察组振荡电位峰值为(37.71±22.23)μV,对照组为(49.70±32.24)μV,差异有统计学意义(P0.05)。观察组视杆反应b波及最大混合反应a波、b波潜伏期与对照组差异均无统计学意义(均为P0.05)。观察组视锥反应a波、b波振幅与对照组差异均无统计学意义(均为P0.05),观察组视锥反应a波、b波潜伏期与对照组差异也均无统计学意义(均为P0.05)。结论经过激光光凝术治疗,ROP患儿视网膜视锥细胞功能发育与正常早产儿没有差别,而视杆细胞功能发育略差。
[Abstract]:Objective to evaluate the changes of retinal function in preterm infants with retinopathy of premature ROP by electroretinogram-ERG (ERG). Methods from January 2011 to December 2012, 30 children with ROP underwent laser photocoagulation in our hospital were selected as observation group, and 30 healthy premature infants with normal retinal development were selected as control group. Dark adaptation and light adaptation ERG were recorded 6 months after laser operation, and the results of the two groups were compared statistically. Results the amplitudes of b wave were 131.47 卤36.20 渭 V in the observation group and 149.33 卤40.14 渭 V in the control group (P 0.05), the amplitudes of a wave B wave in the observation group were 96.52 卤23.71 渭 V and 109.85 卤23.17 渭 V 260.44 卤52.28 渭 V, respectively. The peak value of oscillatory potential was 37.71 卤22.23 渭 V in the control group and 49.70 卤32.24 渭 V in the control group. The difference was statistically significant (P 0.05). There was no significant difference in the latency of wave a and b between the observation group and the control group (P 0.05). There was no significant difference in the amplitude of a wave and b wave between the observation group and the control group (P 0.05), and there was no significant difference in the latency of a wave b wave between the observation group and the control group (all P 0.05). Conclusion the functional development of retinal cone cells in children with ROP treated by laser photocoagulation is not different from that of normal preterm infants, but the development of rod cells is slightly poor.
【作者单位】：中国医科大学附属第四医院眼科;
【分类号】：R779.63

【参考文献】