基于光电容积脉搏波的可穿戴式呼吸率监测系统设计与实验研究

发布时间：2018-05-26 17:45

本文选题：光电容积脉搏波 + 反射式测量　；参考：《北京协和医学院》2017年硕士论文

【摘要】：呼吸率是表征呼吸功能的的一个重要参数,能够提供与人体健康状况相关的重要信息。持续、准确的呼吸率监测有助于预防和识别肺部、呼吸道等部位的病变。临床上主要通过直接测量口部或鼻部的气流,或者利用胸廓和腹部的运动检测,来实现对呼吸率的监测,这些检测方式都具有一定的强迫性,并且设置繁琐,不适于日常生活中使用。利用光电容积脉搏波方法进行呼吸率提取,具有操作简单、无创伤、适用性强等特点。因此实验室拟开发一种可穿戴式运动健康检测设备,试图通过3波长光电传感装置采集人体PPG信号,进而提取蕴含的血氧和呼吸率等生理信息。本文围绕设备的设计需求,进行了两方面的研究:为了研究从利用绿光为光源的PPG信号中提取呼吸率信息的可行性根据人体呼吸和光电容积波的作用规律,设计了以515nm绿光为光源的反射式脉搏信号检测系统,并与热敏电阻采集的参考呼吸信号进行对比测试实验,获得呼吸过慢、呼吸过速、自然呼吸3中呼吸状态下的脉搏信号和同步的参开呼吸信号,利用脉搏差分时间间隔算法提取呼吸率信息,通过统计学方法对数据进行对比分析。结果表明,所设计脉搏呼吸频率提取系统可以完成3种状态下呼吸频率提取,且与参考呼吸频率具有良好的一致性。为了研究在较小的光源-检测器间距下,红光和红外光在固定光学参数的生物组织模拟液中的穿透深度变化情况,以便为检测探头的设计提供参考,搭建了一套用于测量660nm红光和940nm红外光在均一生物组织模型中穿透深度的检测系统,实现在较小的光源-检测器间距范围内,定量地测量两种波长的光在均一的生物组织模拟液中的穿透深度变化情况,测量结果为检测探头的设计提供了很好的参考数据。
[Abstract]:Respiratory rate is an important parameter to characterize respiratory function, which can provide important information related to human health. Continuous and accurate respiratory rate monitoring helps to prevent and identify lesions in the lungs, respiratory tract, etc. In clinic, the respiratory rate is monitored mainly by directly measuring the air flow in the mouth or nose, or by using the movement test of the chest and abdomen. These testing methods are all compulsive and cumbersome. Not suitable for daily use. The method of optoelectronic volumetric pulse wave is used to extract respiratory rate, which has the advantages of simple operation, no trauma and strong applicability. Therefore, the laboratory intends to develop a wearable exercise health detection device, which attempts to collect human PPG signals through a three-wavelength photoelectric sensor device, and then extract physiological information such as blood oxygen and respiration rate. In order to study the feasibility of extracting respiration rate information from PPG signal using green light as light source, according to the action law of human body respiration and photoelectric volume wave, this paper focuses on the design requirements of the equipment. A reflective pulse signal detection system with 515nm green light as light source is designed and compared with the reference respiration signal collected by thermistor. The pulse signal in the breathing state of natural respiration 3 and the synchronous parameterized respiration signal were extracted by using the pulse differential interval algorithm. The data were compared and analyzed by statistical method. The results show that the designed pulse respiratory frequency extraction system can extract the respiratory frequency in three states, and it is in good agreement with the reference respiratory frequency. In order to study the change of penetrating depth of red light and infrared light in biological tissue simulation solution with fixed optical parameters at small light-detector spacing, in order to provide reference for the design of detection probe, A detection system for measuring the penetration depth of 660nm red light and 940nm infrared light in a homogeneous biological tissue model is set up, which is realized in a small range of light-detector spacing. The change of penetration depth of two wavelengths of light in a homogeneous biological tissue simulation solution is quantitatively measured. The results provide a good reference data for the design of the probe.
【学位授予单位】：北京协和医学院
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：TP274;R318

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