循环加载下关节软骨的棘轮应变及理论预测

发布时间：2018-06-02 08:01

本文选题：关节软骨 + 循环压缩　；参考：《医用生物力学》2017年03期

【摘要】：目的获得不同加载条件下关节软骨的棘轮应变,建立预测棘轮应变的理论模型,并对软骨的棘轮应变进行预测。方法将猪股骨远端滑车部的新鲜关节软骨作为研究对象,采用非接触式数字图像技术,测试循环压缩载荷下关节软骨的棘轮应变;建立预测棘轮应变的理论模型,对不同应力幅值和加载率下软骨的棘轮应变进行预测,并比较预测结果与实验结果。结果随循环圈数的增加,软骨的棘轮应变先快速增长然后趋于稳定;定加载率下,软骨的棘轮应变随应力幅值的增大而增大;定应力幅值下,棘轮应变随加载率的增大而减小。实验结果与建立的理论模型预测结果吻合良好。结论关节软骨的棘轮应变与应力幅值成正比,与加载率成反比。建立的理论模型可以预测软骨的棘轮行为,同时为组织工程软骨的构造提供指导。
[Abstract]:Objective to obtain the ratchet strain of articular cartilage under different loading conditions and establish a theoretical model to predict the ratchet strain and predict the ratchet strain of articular cartilage. Methods the fresh articular cartilage of the distal femoral trochlear was used as the research object. The ratchet strain of articular cartilage under cyclic compression load was measured by non-contact digital image technique, and a theoretical model for predicting ratchet strain was established. The ratchet strain of cartilage under different stress amplitude and loading rate was predicted, and the predicted results were compared with the experimental results. Results with the increase of cycle number, the ratchet strain of cartilage first increases rapidly and then tends to stabilize; at constant loading rate, the ratchet strain increases with the increase of stress amplitude, and under constant stress amplitude, ratchet strain decreases with the increase of loading rate. The experimental results are in good agreement with the predicted results of the established theoretical model. Conclusion the ratchet strain of articular cartilage is proportional to the stress amplitude and inversely proportional to the loading rate. The theoretical model can predict the ratchet behavior of cartilage and provide guidance for the construction of tissue engineered cartilage.
【作者单位】：天津理工大学机械工程学院天津市先进机电系统设计与智能控制重点实验室;
【基金】：国家自然科学基金项目(11572222,11432016) 天津市自然科学基金项目(16JCYBJC28400)
【分类号】：R318.01;R684.3

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