3D生物打印技术在组织工程支架构建与再生中的应用进展

发布时间：2018-06-19 01:46

本文选题：D生物打印 + 组织工程　；参考：《航天医学与医学工程》2016年06期

【摘要】：具备个性化、精准化的3D生物打印技术构建优良生物相容性的组织工程支架,替换或修复人体中病变的组织和/或器官,在组织工程研究中极具广泛的应用前景。而作为3D打印技术的基材,如金属、生物陶瓷、高分子材料和细胞生物材料等,也因此得到了研究者的重视和研发。由金属和生物陶瓷制备的支架具有高强度和耐腐蚀性,已在骨科中得到广泛应用,而高分子材料由于其和细胞/组织的良好生物相容性及可塑性使其在软骨、矫形外科、心血管系统等组织/器官中被广泛研究。相信在不久的将来,以上述材料为基材结合3D生物打印技术构建的组织和器官,在临床上会得到应用和推广。本文就用于3D打印的生物材料及其打印技术在组织工程支架构建及组织再生中的应用进行综述。
[Abstract]:Tissue engineering scaffolds with good biocompatibility can be constructed with personalized and accurate 3D biprint technology to replace or repair the diseased tissues and / or organs in human body. It has a wide application prospect in tissue engineering research. As the substrate of 3D printing technology, such as metal, bioceramics, polymer materials and cellular biomaterials, researchers also pay attention to and research. Scaffolds made of metal and bioceramics have been widely used in orthopaedics because of their high strength and corrosion resistance, while polymer materials are widely used in cartilage and orthopedic surgery because of their good biocompatibility and plasticity with cells / tissues. The cardiovascular system and other tissues / organs are widely studied. It is believed that in the near future, the tissue and organs based on the above materials and 3D biologic printing technology will be applied and popularized in clinic. This paper reviews the application of biomaterials and printing technology in tissue engineering scaffold construction and tissue regeneration.
【作者单位】：宁波大学医学院;宁波大学医学院附属第六医院;
【分类号】：R318.6

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