微电极阵列电刺激视网膜的温度场有限元分析

发布时间：2018-06-30 03:03

  本文选题：微电极阵列 + 视网膜　； 参考：《生物医学工程学杂志》2014年06期

【摘要】：为了避免长期电刺激造成视网膜热损伤,本研究旨在探讨使用视网膜假体时电极阵列参数对视网膜温度分布的影响。参照实际的视网膜上假体,用有限元软件(COMSOL Multiphysics)建立4×4微电极阵列电刺激视网膜的三维模型,计算电刺激视网膜时的稳态温度场。分析了电极触点间距、材料与触点半径(即面积)等参数对温度场分布的影响。采用实际刺激电流,视网膜内稳态温度最大增加约0.004℃;电极触点间距从130μm增加到520μm时,温度降低约0.006℃;触点半径从130μm增加到260μm时,温度降低约0.005℃。结果表明,4×4微电极阵列电刺激不会对视网膜造成热损伤。视网膜内的最大温度随着电极触点间距的增加而降低,间距超过触点直径时最大温度之间的差异减少;温度随着触点面积增加而降低;不同电极材料之间的温度差别可忽略。合理地设计电极触点间距和面积可以减少电刺激时的温升。
[Abstract]:In order to avoid retinal thermal injury caused by long-term electrical stimulation, this study was designed to investigate the effect of electrode array parameters on retinal temperature distribution when retinal prosthesis was used. According to the actual supraretinal prosthesis, a three-dimensional model of 4 脳 4 microelectrode array was established by finite element software (COMSOL Multiphysics) to calculate the steady-state temperature field of retina. The effects of contact distance, material and contact radius (i.e. area) on the temperature field distribution are analyzed. The maximum increase of steady-state temperature in retina is about 0.004 鈩，

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