生物组织的太赫兹数字全息成像
发布时间：2018-07-24 18:53
【摘要】：太赫兹辐射具有低光子能量和较高的透射性,并对水分子等极性物质反应敏感,因此太赫兹数字全息成像法可以快速准确地获取生物组织信息。本文利用太赫兹数字全息成像系统对猪肉和羊肉组织切片进行测量,采用菲涅耳反衍射方法对实验结果进行优化,选取0.9THz分量的振幅图像进行分析。通过计算组织的吸光度获取0.9THz吸光度图像。实验结果显示,肌肉组织的吸光度均在8cm~(-1)以上,脂肪组织的吸光度不超过4cm~(-1)。采用主成分分析方法获得吸光度得分图并进行重建,从重建结果中可以清晰区分生物组织的不同区域。由此表明,太赫兹数字全息成像技术能够直接获取生物组织的二维信息,探测时间短、效率高,在生物检测领域具有广阔的应用前景。
[Abstract]:Terahertz radiation has low photon energy and high transmittance, and is sensitive to the reaction of polar materials such as water molecules. Therefore, terahertz digital holographic imaging method can obtain tissue information quickly and accurately. In this paper, THz digital holographic imaging system is used to measure pork and mutton tissue slices, Fresnel inverse diffraction method is used to optimize the experimental results, and the amplitude images of 0.9THz component are selected for analysis. The absorbance image of 0.9THz was obtained by calculating the absorbance of tissue. The results showed that the absorbance of muscle tissue was above 8 cm ~ (-1), and that of adipose tissue was less than 4 cm ~ (-1). The absorbance score map was obtained by principal component analysis (PCA) and reconstructed. Different regions of biological tissue could be clearly distinguished from the reconstruction results. It is shown that terahertz digital holographic imaging technology can directly obtain the two-dimensional information of biological tissue, and the detection time is short, the efficiency is high, and it has a broad application prospect in the field of biological detection.
【作者单位】： 首都师范大学物理系;
【基金】：国家自然科学基金资助项目(No.11474206)
【分类号】：Q6-3;O441.4;R310
[Abstract]:Terahertz radiation has low photon energy and high transmittance, and is sensitive to the reaction of polar materials such as water molecules. Therefore, terahertz digital holographic imaging method can obtain tissue information quickly and accurately. In this paper, THz digital holographic imaging system is used to measure pork and mutton tissue slices, Fresnel inverse diffraction method is used to optimize the experimental results, and the amplitude images of 0.9THz component are selected for analysis. The absorbance image of 0.9THz was obtained by calculating the absorbance of tissue. The results showed that the absorbance of muscle tissue was above 8 cm ~ (-1), and that of adipose tissue was less than 4 cm ~ (-1). The absorbance score map was obtained by principal component analysis (PCA) and reconstructed. Different regions of biological tissue could be clearly distinguished from the reconstruction results. It is shown that terahertz digital holographic imaging technology can directly obtain the two-dimensional information of biological tissue, and the detection time is short, the efficiency is high, and it has a broad application prospect in the field of biological detection.
【作者单位】： 首都师范大学物理系;
【基金】：国家自然科学基金资助项目(No.11474206)
【分类号】：Q6-3;O441.4;R310
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