多通道经颅磁刺激线圈阵列的驱动与控制

发布时间：2018-08-13 18:58

【摘要】：经颅磁刺激是一种无痛、无创的神经刺激技术,近年来在医学上被广泛使用。与传统单通道磁刺激线圈相比,多通道线圈阵列可以实现多点同步刺激、扫描刺激以及刺激模式的灵活切换,因此具有更好的发展前景。但由于线圈阵列驱动电路复杂、线圈间存在电磁耦合等难点,多通道线圈阵列的驱动与控制方法仍需进一步研究。该文基于8路独立导线构成的4×4直导线阵列,设计了一种新颖的多通道线圈阵列的驱动与控制电路。驱动电路主要包括充电电路和8路放电电路,用于在线圈阵列中产生脉冲电流;控制电路则主要用于切换刺激模式和控制脉冲电流的幅值及重复频率。通过仿真计算和实验测量,分析电磁耦合对脉冲电流波形的影响,验证了该驱动与控制电路可以实现线圈阵列在不同重复频率、不同刺激模式下工作,并且在理论上,线圈阵列下方3cm处的刺激强度足够达到脑细胞的兴奋阈值。
[Abstract]:Transcranial magnetic stimulation (TMS) is a painless and non-invasive technique of nerve stimulation, which has been widely used in medicine in recent years. Compared with the traditional single-channel magnetic stimulation coil, the multi-channel coil array can realize multi-point synchronous stimulation, scanning stimulation and flexible switching of stimulation mode, so it has a better development prospect. However, because of the complexity of the coil array driving circuit and the difficulties of electromagnetic coupling between the coils, the drive and control methods of the multi-channel coil array still need to be further studied. Based on 4 脳 4 straight conductor array composed of 8 independent conductors, a novel drive and control circuit of multi-channel coil array is designed in this paper. The driving circuit mainly includes charging circuit and 8-channel discharge circuit, which is used to generate pulse current in coil array, while the control circuit is mainly used to switch the stimulation mode and control the amplitude and repetition rate of pulse current. The effect of electromagnetic coupling on pulse current waveform is analyzed by simulation and experimental measurement. It is verified that the drive and control circuit can realize the coil array working at different repetitive frequencies and different stimulation modes. The stimulation at the 3cm below the coil array is strong enough to reach the threshold of brain cell excitation.
【作者单位】：西安交通大学电气工程学院;
【分类号】：R318;TM55

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