一种与N-Back诱发脑力疲劳相关的特异性脑电网络结构

发布时间：2018-08-28 08:37

【摘要】：探究脑力疲劳引起的静息态脑电网络结构的改变,以及体力疲劳的引入对脑力疲劳相关脑电网络的影响。分别以2-back实验和功率自行车诱发脑力、体力疲劳,采集10名被试脑力疲劳前后以及体脑疲劳前后4种状态下20个导联的静息脑电信号(EEG),进行偏定向相干因果性分析。对被试的脑电网络连接逐个进行威尔科克森符号秩检验,选择PDC值显著性大于阈值的连接赋为1,构建出二值化脑电网络。通过对疲劳前后脑电网络的比较与拆分计算,提取出一个N-back实验下与脑力疲劳相关的特异性脑电网络结构,该网络以额区的FP2导联为中枢节点,呈现出由全脑所有导联指向FP2的规律。在脑力疲劳和体脑疲劳两种疲劳状态下,该网络的连接形式基本保持一致,连接系数分别是4.060 3和4.142 1,没有发生显著改变,所以是一种相对独立、稳定并与脑力疲劳密切相关的功能网络。该方法和结果有望为研究脑力疲劳和探索体脑疲劳交互影响机制提供一个新的视角。
[Abstract]:This paper explores the changes of resting EEG network structure caused by mental fatigue and the influence of physical fatigue on brain fatigue related EEG network. Mental and physical fatigue were induced by 2-back experiment and power bicycle. (EEG), of 20 leads were collected from 10 subjects before and after brain fatigue and 4 states before and after body brain fatigue for directional coherence causality analysis. Wilcokson's sign rank test was performed on the EEG network connections of the subjects, and a binary-valued EEG network was constructed by selecting the connection with a significant PDC value greater than the threshold value of 1. By comparing and splitting the EEG network before and after fatigue, a specific EEG network structure related to mental fatigue was extracted in N-back experiment. The FP2 lead in the frontal region was used as the central node in the network. There is a pattern of all leads pointing to FP2 in the whole brain. Under the condition of mental fatigue and body-brain fatigue, the connection forms of the network are basically the same, and the connection coefficients are 4.060 3 and 4.142 1, respectively. The connection coefficient is not changed significantly, so it is relatively independent. A functional network that is stable and closely related to mental fatigue. This method and results are expected to provide a new perspective for the study of the interaction between mental fatigue and body-brain fatigue.
【作者单位】：天津大学精密仪器与光电子工程学院生物医学工程系;
【基金】：国家自然科学基金重大研究计划(91520205);国家自然科学基金(81571762);国家自然科学基金(31500865)
【分类号】：R318;TN911.7

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