一种新型水浴冷冻夹具在大鼠跟腱力学测试中的应用

发布时间：2018-10-14 15:13

【摘要】：设计一种新型的冷冻水浴型夹具,用于解决大鼠跟腱力学测试的问题。以SD大鼠肌肉-跟腱-跟骨为单元的样本随机分成A、B两组。A组:大鼠跟腱样本采用设计的新型水浴型冷冻夹具;B组:大鼠跟腱样本采用传统非水浴冷冻夹具。结果显示,在力学测试过程中,A组样本无一滑脱,跟腱处于生理活性状态;B组样本有一根滑脱,其他样本跟腱有明显被冷冻现象。A组样本平均最大应力、最大断裂点位移以及杨氏模量较B组差异均有统计学意义(P0.05)。实验结果表明,新的冷冻水浴型夹具优于传统非水浴条件冷冻夹具,能够更好地模拟体内环境条件测试跟腱的力学性质。
[Abstract]:A new type of frozen water bath fixture was designed to solve the problem of mechanical testing of Achilles tendon in rats. The samples of SD rats were randomly divided into two groups: group A: the calcaneal tendon was frozen with a new type of water bath clamp designed, and group B: the samples of Achilles tendon were frozen with traditional non-water bath clamp. The results showed that during the mechanical test, the samples of group A had no slippage and the Achilles tendons were in a state of physiological activity, group B had one slippage and the other samples were obviously frozen. The maximum fracture point displacement and Young's modulus were significantly different from group B (P0.05). The experimental results show that the new chilled water bath fixture is superior to the traditional non-water bath freezing fixture and can better simulate the environmental conditions in vivo to test the mechanical properties of Achilles tendon.
【作者单位】： "生物流变科学与技术"教育部重点实验室&重庆大学生物工程学院国家"111计划"基地;东风汽车公司技术中心;重庆市公安局物证鉴定中心;
【基金】：高等学校学科创新引智计划资助项目(国家“111计划”)(B06023) 国家自然科学基金资助项目(11032012,31270990) 新世纪优秀人才支持计划资助项目(NCET-10-0879) 重庆大学大型仪器设备开放基金资助项目
【分类号】：R318.01

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