不同扩张尺度对非对称椎动脉支架力学性能影响的研究

发布时间：2018-10-18 11:47

【摘要】：在临床治疗中,不同尺寸的狭窄血管所需要支架扩张的尺度也不同,而支架的扩张尺度对其力学性能有着重要影响。利用有限元方法仿真模拟分析了三款不同支架的体外扩张过程,主要研究了结构相同时不同扩张尺度对支架力学性能的影响。结果显示:随着支架扩张直径的增大,支架的最大等效应力、轴向短缩率、扩张不均匀性及柔顺性能呈递增趋势,支撑刚度和静安全系数呈递减趋势;支架的径向回弹主要受到其材料和结构影响,扩张尺度并不起决定性作用;通过与实验结果相比对,理论值与实验值结果吻合较好,误差在7%以内,验证了有限元模拟的准确性及合理性;利用动物实验对支架治疗效果进行验证,表明了支架的植入治疗是安全且有效的。综合考虑各因素影响,支架的治疗效果受支架扩张尺度的影响较大,这为临床治疗的顺利实施提供了良好的理论依据。
[Abstract]:In clinical treatment, the dilation scale of stent is different for different sizes of stenosis vessels, and the scale of stent dilatation has an important effect on its mechanical properties. The in vitro expansion process of three different scaffolds was simulated by finite element method, and the effects of different dilatation scales on the mechanical properties of the scaffolds were studied. The results show that the maximum equivalent stress, axial shortening rate, expansion inhomogeneity and compliance are increasing with the increase of the expansion diameter, and the support stiffness and static safety factor are decreasing. The radial springback of the scaffold is mainly affected by its material and structure, and the expansion scale does not play a decisive role. By comparing with the experimental results, the theoretical values agree well with the experimental results, and the error is less than 7%. The accuracy and rationality of finite element simulation are verified, and the effect of stent implantation is verified by animal experiments, which shows that the stent implantation is safe and effective. Considering the influence of various factors, the therapeutic effect of stent is greatly affected by the scale of stent expansion, which provides a good theoretical basis for the successful implementation of clinical treatment.
【作者单位】：内蒙古工业大学机械学院;
【基金】：国家自然科学基金项目(81160186) 内蒙古自治区自然科学基金项目(2015MS0803)
【分类号】：R651.12;R318.01

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