无针注射器技术研究
发布时间：2018-11-09 10:43
【摘要】：无针注射是利用药液的高速射流进入被注射体内,从而完成注射的技术过程。随着临床需要的推动和科学技术的发展,无针注射器技术呈现出蓬勃发展的态势,美国和欧洲已经有不同类型的商品面世,我国对无针注射的研究刚刚起步,目前还没有针对国内需求的产品上市。 本文主要研究的内容如下： 1.介绍了国内外已有的无针注射器技术,总结了现有无针注射器的技术指标及研究开发路线； 2.进行无针注射器总体方案的设计,根据功能,将无针注射器分为机械结构部分、液压回路部分和电气控制部分,对各部分分析并确定最终采用的方案； 3.根据分析及要求细化结构,对关键参数进行理论计算,设计得到产品三维模型,并且简化设计原理样机,验证无针注射器原理的可行性； 4.基于前人设计的小孔喷射模型和液体撞击模型,对设计的机器进行仿真,得到对于各个高压空气弹簧的喷射特性分布； 5.进行稳定性实验、高速摄像实验、注射仿生材料实验以及离体猪肉注射实验,四个实验层层递进,逐步证实了无针注射器原理样机的稳定性、模型仿真数据与实验数据的吻合度以及注射形态稳定性,并且验证了随着注射动力的增加,注射深度随之增加的结论。 本文设计了机械机构、电气控制,对喷射过程进行理论分析,加工调试样机,并开展了多种实验,验证了样机的可行性和可靠性,完成了新产品开发的前期工作,为后续的新产品开发的完善奠定了坚实的基础。
[Abstract]:Needle-free injection is the technical process of injection by using the high-speed jet of the liquid into the injected body. With the promotion of clinical needs and the development of science and technology, needle free syringe technology has shown a vigorous development trend, the United States and Europe have been different types of commodities, the study of needle free injection in China has just started. At present, there is no domestic demand for products on the market. The main contents of this paper are as follows: 1. This paper introduces the existing syringe technology at home and abroad, summarizes the technical index and research and development route of the existing syringe. 2. According to the function, the syringe is divided into mechanical structure part, hydraulic circuit part and electrical control part. According to the analysis and the requirement to refine the structure, the key parameters are calculated theoretically, the product 3D model is designed, and the prototype of the design principle is simplified to verify the feasibility of the principle of the needle less syringe. 4. Based on the small hole injection model and liquid impact model designed by predecessors, the designed machine is simulated and the spray characteristic distribution for each high-pressure air spring is obtained. 5. The stability experiment, high speed camera experiment, injection bionic material experiment and in vitro pork injection experiment were carried out. Four experiments were carried out step by step, which gradually proved the stability of the principle prototype of the needle free syringe. The consistency of the model simulation data with the experimental data and the stability of the injection morphology are verified, and the conclusion that the injection depth increases with the increase of the injection power is verified. In this paper, the mechanical mechanism, electrical control, theoretical analysis of the injection process, processing and debugging of the prototype are designed, and a variety of experiments are carried out to verify the feasibility and reliability of the prototype, and the preliminary work of the new product development is completed. For the subsequent development of new products to establish a solid foundation.
【学位授予单位】：浙江大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：TH789
本文编号：2320173
[Abstract]:Needle-free injection is the technical process of injection by using the high-speed jet of the liquid into the injected body. With the promotion of clinical needs and the development of science and technology, needle free syringe technology has shown a vigorous development trend, the United States and Europe have been different types of commodities, the study of needle free injection in China has just started. At present, there is no domestic demand for products on the market. The main contents of this paper are as follows: 1. This paper introduces the existing syringe technology at home and abroad, summarizes the technical index and research and development route of the existing syringe. 2. According to the function, the syringe is divided into mechanical structure part, hydraulic circuit part and electrical control part. According to the analysis and the requirement to refine the structure, the key parameters are calculated theoretically, the product 3D model is designed, and the prototype of the design principle is simplified to verify the feasibility of the principle of the needle less syringe. 4. Based on the small hole injection model and liquid impact model designed by predecessors, the designed machine is simulated and the spray characteristic distribution for each high-pressure air spring is obtained. 5. The stability experiment, high speed camera experiment, injection bionic material experiment and in vitro pork injection experiment were carried out. Four experiments were carried out step by step, which gradually proved the stability of the principle prototype of the needle free syringe. The consistency of the model simulation data with the experimental data and the stability of the injection morphology are verified, and the conclusion that the injection depth increases with the increase of the injection power is verified. In this paper, the mechanical mechanism, electrical control, theoretical analysis of the injection process, processing and debugging of the prototype are designed, and a variety of experiments are carried out to verify the feasibility and reliability of the prototype, and the preliminary work of the new product development is completed. For the subsequent development of new products to establish a solid foundation.
【学位授予单位】：浙江大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：TH789
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