基于脉搏色素光密度法的心输出量测量系统
发布时间：2018-11-11 09:52
【摘要】：临床上心输出量(CO)等心血管血流动力学参数是心脏功能状况及心血管疾病的诊断依据,传统CO检测方法操作繁杂、有创伤以及患者术后易引发并发症。针对此问题,研究了一种基于脉搏色素光密度法的心输出量测量系统,以朗伯比尔定律和色素稀释理论为基础,通过选取合适的双波长探测光源(805nm/940 nm)实现了动脉吲哚氰绿(ICG)色素浓度谱的无创实时测量,从ICG浓度稀释曲线中计算出CO的数值。将本系统测量的值与当前测量CO的金标准热稀释法的结果进行对比,平均误差为4.79%,相关系数为0.99。实验结果表明:本研究所设计的心输出量测量系统实现了CO的无创、准确测量,可为临床检测CO提供一种新的选择。
[Abstract]:Cardiovascular hemodynamic parameters such as cardiac output (CO) are the basis for the diagnosis of cardiac function and cardiovascular disease. Traditional CO detection methods are complicated and have trauma and complications after operation. In order to solve this problem, a heart output measurement system based on pulse pigment optical density method is studied, which is based on Lambert's law and pigment dilution theory. The non-invasive real-time measurement of the concentration spectrum of indocyanine green (ICG) pigment in arterial indocyanine green was realized by selecting suitable dual-wavelength detection light source (805nm/940 nm). The value of CO was calculated from the dilution curve of ICG concentration. The average error of the system is 4.79 and the correlation coefficient is 0.99, compared with the results obtained by the current gold standard thermal dilution method for CO measurement. The experimental results show that the cardiac output measurement system designed in this paper realizes the noninvasive and accurate measurement of CO, which provides a new choice for clinical detection of CO.
【作者单位】： 北华大学工程训练中心;北华大学电气信息工程学院;吉林大学仪器科学与电气工程学院;
【基金】：国家“十二五”科技支撑计划(2015BAI02B04) 吉林省发改委省级产业创新专项资金项目(2016C052-2) 吉林省教育厅“十二五”科学技术研究规划重点项目(440020031134);吉林省教育厅科学研究规划项目(JJKH20170034KJ,JJKH20170035KJ)
【分类号】：R318.6
本文编号：2324483
[Abstract]:Cardiovascular hemodynamic parameters such as cardiac output (CO) are the basis for the diagnosis of cardiac function and cardiovascular disease. Traditional CO detection methods are complicated and have trauma and complications after operation. In order to solve this problem, a heart output measurement system based on pulse pigment optical density method is studied, which is based on Lambert's law and pigment dilution theory. The non-invasive real-time measurement of the concentration spectrum of indocyanine green (ICG) pigment in arterial indocyanine green was realized by selecting suitable dual-wavelength detection light source (805nm/940 nm). The value of CO was calculated from the dilution curve of ICG concentration. The average error of the system is 4.79 and the correlation coefficient is 0.99, compared with the results obtained by the current gold standard thermal dilution method for CO measurement. The experimental results show that the cardiac output measurement system designed in this paper realizes the noninvasive and accurate measurement of CO, which provides a new choice for clinical detection of CO.
【作者单位】： 北华大学工程训练中心;北华大学电气信息工程学院;吉林大学仪器科学与电气工程学院;
【基金】：国家“十二五”科技支撑计划(2015BAI02B04) 吉林省发改委省级产业创新专项资金项目(2016C052-2) 吉林省教育厅“十二五”科学技术研究规划重点项目(440020031134);吉林省教育厅科学研究规划项目(JJKH20170034KJ,JJKH20170035KJ)
【分类号】：R318.6
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