光纤传输调Q铥激光微外科手术刀切割生物软组织实验研究
发布时间:2018-12-11 12:48
【摘要】:为了评估光纤传输波长为2.013μm的调Q铥激光作为微外科手术刀的可行性,研究200μm芯径的光纤传输频率为1kHz、脉宽为400~1400ns的调Q铥激光在不同能量和不同切割速度条件下切割新鲜猪肾组织的性能。采用专业相机拍摄组织切割后的切割线形貌,光学显微镜拍摄组织切片凹坑形貌,使用科学图像分析软件测量凹坑形貌参数,数据统计分析软件分析实验数据。结果表明相同能量条件下切割速度越大,切割效果越不明显。相同切割速度时,激光脉冲能量越大切割效果越明显。光纤传输高频调Q的铥激光可期望作为微外科手术刀在临床上得到应用。
[Abstract]:In order to evaluate the feasibility of using Q-switched thulium laser with a wavelength of 2.013 渭 m as a microsurgical scalpel, the transmission frequency of fiber with a core diameter of 200 渭 m is 1 kHz. The performance of Q-switched thulium laser with pulse width of 400~1400ns in cutting fresh porcine kidney at different energy and cutting speed. The cut line morphology of tissue was photographed by professional camera and the concave morphology of tissue slice was photographed by optical microscope. The morphological parameters of the tissue were measured by scientific image analysis software and the experimental data were analyzed by statistical analysis software. The results show that the higher the cutting speed under the same energy condition, the less obvious the cutting effect is. At the same cutting speed, the larger the laser pulse energy is, the more obvious the cutting effect is. Thulium laser can be used as microsurgical scalpel in clinic.
【作者单位】: 中国地质大学(武汉)数理学院;中国科学院苏州生物医学工程技术研究所江苏省医用光学重点实验室;中国地质大学(武汉)地质过程与矿产资源国家重点实验室;
【基金】:武汉市青年科技晨光计划(201271031430) 中国博士后科学基金面上项目(2014M2104) 江苏省医用光学重点实验室开放基金(JKLMO201405) 中央高校基本科研业务费专项资金
【分类号】:R318.51
[Abstract]:In order to evaluate the feasibility of using Q-switched thulium laser with a wavelength of 2.013 渭 m as a microsurgical scalpel, the transmission frequency of fiber with a core diameter of 200 渭 m is 1 kHz. The performance of Q-switched thulium laser with pulse width of 400~1400ns in cutting fresh porcine kidney at different energy and cutting speed. The cut line morphology of tissue was photographed by professional camera and the concave morphology of tissue slice was photographed by optical microscope. The morphological parameters of the tissue were measured by scientific image analysis software and the experimental data were analyzed by statistical analysis software. The results show that the higher the cutting speed under the same energy condition, the less obvious the cutting effect is. At the same cutting speed, the larger the laser pulse energy is, the more obvious the cutting effect is. Thulium laser can be used as microsurgical scalpel in clinic.
【作者单位】: 中国地质大学(武汉)数理学院;中国科学院苏州生物医学工程技术研究所江苏省医用光学重点实验室;中国地质大学(武汉)地质过程与矿产资源国家重点实验室;
【基金】:武汉市青年科技晨光计划(201271031430) 中国博士后科学基金面上项目(2014M2104) 江苏省医用光学重点实验室开放基金(JKLMO201405) 中央高校基本科研业务费专项资金
【分类号】:R318.51
【共引文献】
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