3D打印技术构建左心室磁悬浮辅助泵模型研究
发布时间：2019-05-29 00:40
【摘要】：左心室辅助装置作为一款心室辅助装置,已成为人们关注的焦点。目前国内外对左心室磁悬浮辅助装置的相关研究较多,溶血性能和血栓是评价血泵性能好坏的重要标准,具备良好的溶血性能和较低的血栓发生率不仅可以提高辅助装置的安全性,而且还能为研制永久性植入式左心室磁悬浮辅助装置奠定基础。本文以自主研发的左心室磁悬浮辅助泵为研究对象,利用计算流体力学模拟左心室磁悬浮辅助装置内部叶片与血液的耦合过程,研究叶片个数、叶片高度、悬浮高度,以及叶片转速对血流动力学的影响。应用3D打印技术对设计装置进行加工制造并进行实验,为今后的相关实验研究提供参考了依据。理论研究结果表明:耦合过程中叶片的转速对血泵出口流量和叶片壁面剪切应力的影响最大,叶片个数和高度次之,悬浮高度最小;提高叶片转速,叶片壁面最大剪切应力和血泵出口平均流量将会增加;增加叶片个数,叶片最大剪切应力会出现增加的趋势;增加叶片高度,叶片最大剪切应力将减少,出口平均流量将增加;增加悬浮高度,叶片最大剪切应力和出口平均流量均会减少;随着悬浮高度增加,靠近叶片结构间的主要流迹分布有减少的趋势;随着叶片高度增加,血流的主要流迹趋于规则化,没有形成涡流区和回流区,但叶片高度过高,血流流迹流经叶片结构根部的趋势会逐渐减小,不利于防止血栓的产生;叶片转速对血流流迹的分布影响较小。利用计算流体模拟仿真软件对左心室磁悬浮辅助装置进行研究,揭示了血泵与血液相互作用的影响规律,为辅助装置结构优化奠定了理论基础。实验结果显示,3D打印技术制造的辅助泵满足了实验的需要,并为医疗领域应用3D打印技术提供了一种新思路。
[Abstract]:As a ventricular auxiliary device, left ventricular auxiliary device has become the focus of attention. At present, there are many researches on left ventricular maglev auxiliary device at home and abroad. Hemolytic performance and thrombus are important standards to evaluate the performance of blood pump. Good hemolytic performance and low thrombus incidence can not only improve the safety of auxiliary device, but also lay a foundation for the development of permanent implantable left ventricular maglev auxiliary device. In this paper, the coupling process between blade and blood in left ventricular maglev auxiliary device is simulated by computational fluid dynamics (CFD), and the number of blades, blade height and suspension height are studied. And the effect of blade speed on hemodynamics. 3D printing technology is used to process and manufacture the design device and carry on the experiment, which provides a reference for the related experimental research in the future. The theoretical results show that the rotating speed of the blade has the greatest influence on the outlet flow rate of the blood pump and the shear stress on the blade wall, followed by the number and height of the blade, and the suspension height is the smallest. With the increase of blade speed, the maximum shear stress on the blade wall and the average flow rate at the outlet of the blood pump will increase, and the maximum shear stress of the blade will increase with the increase of the number of blades. With the increase of blade height, the maximum shear stress of blade will decrease and the average flow rate at outlet will increase, and with the increase of suspension height, the maximum shear stress and outlet average flow rate of blade will decrease. With the increase of suspension height, the distribution of main flow tracks near the blade structure tends to decrease. With the increase of blade height, the main flow trace of blood flow tends to be regular, and no vortex area and reflux area are formed, but when the blade height is too high, the trend of blood flow trace flow through the root of blade structure will gradually decrease, which is not conducive to preventing the formation of thrombus. The blade speed has little effect on the distribution of blood flow trace. The left ventricular maglev auxiliary device is studied by using computational fluid simulation software, and the influence law of the interaction between blood pump and blood is revealed, which lays a theoretical foundation for the structural optimization of the auxiliary device. The experimental results show that the auxiliary pump manufactured by 3D printing technology meets the needs of the experiment and provides a new idea for the application of 3D printing technology in medical field.
【学位授予单位】：内蒙古工业大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R318.6;TP391.73
[Abstract]:As a ventricular auxiliary device, left ventricular auxiliary device has become the focus of attention. At present, there are many researches on left ventricular maglev auxiliary device at home and abroad. Hemolytic performance and thrombus are important standards to evaluate the performance of blood pump. Good hemolytic performance and low thrombus incidence can not only improve the safety of auxiliary device, but also lay a foundation for the development of permanent implantable left ventricular maglev auxiliary device. In this paper, the coupling process between blade and blood in left ventricular maglev auxiliary device is simulated by computational fluid dynamics (CFD), and the number of blades, blade height and suspension height are studied. And the effect of blade speed on hemodynamics. 3D printing technology is used to process and manufacture the design device and carry on the experiment, which provides a reference for the related experimental research in the future. The theoretical results show that the rotating speed of the blade has the greatest influence on the outlet flow rate of the blood pump and the shear stress on the blade wall, followed by the number and height of the blade, and the suspension height is the smallest. With the increase of blade speed, the maximum shear stress on the blade wall and the average flow rate at the outlet of the blood pump will increase, and the maximum shear stress of the blade will increase with the increase of the number of blades. With the increase of blade height, the maximum shear stress of blade will decrease and the average flow rate at outlet will increase, and with the increase of suspension height, the maximum shear stress and outlet average flow rate of blade will decrease. With the increase of suspension height, the distribution of main flow tracks near the blade structure tends to decrease. With the increase of blade height, the main flow trace of blood flow tends to be regular, and no vortex area and reflux area are formed, but when the blade height is too high, the trend of blood flow trace flow through the root of blade structure will gradually decrease, which is not conducive to preventing the formation of thrombus. The blade speed has little effect on the distribution of blood flow trace. The left ventricular maglev auxiliary device is studied by using computational fluid simulation software, and the influence law of the interaction between blood pump and blood is revealed, which lays a theoretical foundation for the structural optimization of the auxiliary device. The experimental results show that the auxiliary pump manufactured by 3D printing technology meets the needs of the experiment and provides a new idea for the application of 3D printing technology in medical field.
【学位授予单位】：内蒙古工业大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R318.6;TP391.73
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